Hiroshima University Syllabus

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Japanese
Academic Year 2026Year School/Graduate School Graduate School of Biomedical and Health Sciences (Master’s Course)
Lecture Code TB002001 Subject Classification Specialized Education
Subject Name バイオインフォマティクス入門
Subject Name
(Katakana)
バイオインフォマティクスニュウモン
Subject Name in
English
Introduction to Bioinformatics
Instructor HAYES CLAIR NELSON,NAKAHARA HIKARU
Instructor
(Katakana)
ヘイズ クレアーネルソン,ナカハラ ヒカル
Campus Kasumi Semester/Term 1st-Year,  First Semester,  1Term
Days, Periods, and Classrooms (1T) Tues11-12
Lesson Style Lecture Lesson Style
(More Details)
Face-to-face
Lecture-based, exercise-based, discussion-based 
Credits 1.0 Class Hours/Week 2 Language of Instruction B : Japanese/English
Course Level 7 : Graduate Special Studies
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 04 : Life Sciences
Eligible Students Students interested in data analysis
Keywords bioinformatics, data science, genomics, transcriptomics, Linux, R 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students)
 
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students)
 
Class Objectives
/Class Outline
Modern biomedical and life science research increasingly relies on computational tools to analyze large-scale experimental data. This introductory course provides graduate students with foundational skills in bioinformatics, focusing on key methods and practical applications. Students will learn to perform sequence similarity searches using BLAST, conduct DNA sequence alignment for variant identification, and analyze RNA-seq data for differential gene expression. The course also introduces essential computational environments for bioinformatics, including the Linux command line and RStudio for statistical analysis and data visualization. Classes will meet for eight three-hour sessions. Each session will include a lecture taught in English and Japanese to introduce core concepts, followed by a hands-on workshop where students will apply what they have learned through guided exercises using real biological data. 
Class Schedule 1) 4/14 Review of concepts in DNA/RNA biology and introduction to genome browsers and life sciences databases
2) 4/21 Introduction to Linux
3) 4/28 DNA/RNA sequencing and alignment
4) 5/7 Alignment to a reference genome for variant calling
5) 5/12 RNA sequence alignment and quantification
6) 5/19 Introduction to R
7) 5/26 Differential gene expression analysis
8) 6/2 Gene set enrichment analysis
 
Text/Reference
Books,etc.
Learning materials will be provided during the course. 
PC or AV used in
Class,etc.
Text, Handouts, Audio Materials, Visual Materials
(More Details)  
Learning techniques to be incorporated Discussions, Quizzes/ Quiz format, Project Learning
Suggestions on
Preparation and
Review
The course project is intended to help guide students in learning the specific skills needed for their current or planned research. 
Requirements A PC capable of connecting to the Internet. 
Grading Method Attendance, proactive learning attitude, assignments in class 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message  
Other   
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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