K7369030 Biochemical Engineering

Hiroshima University Syllabus

Japanese

Academic Year 2026Year School/Graduate School School of Engineering

Lecture Code K7369030 Subject Classification Specialized Education

Subject Name 培養技術論

Subject Name
（Katakana）バイヨウギジユツロン

Subject Name in
English Biochemical Engineering

Instructor HIROTA RYUICHI

Instructor
(Katakana) ヒロタ　リュウイチ

Campus Higashi-Hiroshima Semester/Term 3rd-Year, First Semester, 2Term

Days, Periods, and Classrooms (2T) Tues3-4,Thur3-4：ENG 106

Lesson Style Lecture Lesson Style
(More Details) Face-to-face, Online (on-demand)

Basically, face-to-face lecture. When lecture is not possible, online lecture will be done.

Credits 2.0 Class Hours/Week 4 Language of Instruction B : Japanese／English

Course Level 3 : Undergraduate High-Intermediate

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 02 : Biotechnology

Eligible Students Junior students in Faculty of Engineering Cluster 3

Keywords Fermentation Technology, Fermentative production, Microorgamisms, Bioproduction, Biotechnology

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) This class is classified as "Applied Biological Science" in specialized course in Faculty of Engineering Cluster 3. In this class, theoretical bases on Feretemntation Technology experimantal trainig in Biotechnological experimental training course will be learned. Therefore, you should take Biotechnological experimental training course. And to comprehensively learn fermentation technology, it is highly recommended to take Fermentation Technology class.
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) Program of Biotechnology
（Knowledge and Understanding）
・Acquisition of basic and advanced knowledge relating to biotechnology and life science. (Target/Lecture class)

Class Objectives
/Class Outline The aim is to learn basic knowledge on unit processes in modern fermentation technology. This class will give you theretical aspects on fermentation technology, while you will learn their practical aspects in Biotechnological experimental training course.

Class Schedule lesson1 Introduction: What Do We Learn in Cultivation Technology?
lesson2 Culture Media: Nutritional Requirements of Microorganisms
lesson3 Microbial Energy Metabolism
lesson4 Cultivation Methods I: Batch Culture
lesson5 Batch Culture (Exercises)
lesson6 Cultivation Methods II: Continuous Culture
lesson7 Continuous Culture (Exercises)
lesson8 Aeration and Agitation in Bioreactors
lesson9 Aeration and Agitation (Exercises)
lesson10 Cultivation Methods III: Fed-Batch Culture
lesson11 Fed-Batch Culture (Exercises)
lesson12 Sterilization Kinetics (Lecture and Exercises)
lesson13 Strain Development
lesson14 Amino Acid Fermentation
lesson15 Modern Technologies for Controlling Microbial Growth

Text/Reference
Books,etc. P. F. Stanbury and A. Whitaker. Principles of Fermentation Technology. Pergamon Press Ltd.

PC or AV used in
Class,etc. Text

(More Details)

Learning techniques to be incorporated Quizzes/ Quiz format, Post-class Report

Suggestions on
Preparation and
Review 1–3) Students will learn the theoretical foundations of microbial growth and energy metabolism, with reference to related subjects such as Biochemistry I and Fermentation Engineering.

4–12) Each class unit will include both lectures and exercises. For the exercises, problems will be assigned through Moodle in the previous class, and students are expected to complete them before the next class. Reports should also be submitted through Moodle.

4–7) The theoretical background and exercises related to batch culture experiments conducted in the student laboratory course (Cultivation Engineering Laboratory) will be covered.

13–15) Students will learn applied aspects of cultivation technology, including the principles of strain improvement used in modern fermentation production and practical approaches to microbial cultivation.

Requirements

Grading Method The final exam: 80%, homeworks: 20%

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2026Year	School/Graduate School	School of Engineering
Lecture Code	K7369030	Subject Classification	Specialized Education
Subject Name	培養技術論
Subject Name （Katakana）	バイヨウギジユツロン
Subject Name in English	Biochemical Engineering
Instructor	HIROTA RYUICHI
Instructor (Katakana)	ヒロタ　リュウイチ
Campus	Higashi-Hiroshima	Semester/Term	3rd-Year, First Semester, 2Term
Days, Periods, and Classrooms	(2T) Tues3-4,Thur3-4：ENG 106
Lesson Style	Lecture	Lesson Style (More Details)	Face-to-face, Online (on-demand)
Basically, face-to-face lecture. When lecture is not possible, online lecture will be done.
Credits	2.0	Class Hours/Week	4	Language of Instruction	B : Japanese／English
Course Level	3 : Undergraduate High-Intermediate
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	02 : Biotechnology
Eligible Students	Junior students in Faculty of Engineering Cluster 3
Keywords	Fermentation Technology, Fermentative production, Microorgamisms, Bioproduction, Biotechnology
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)	This class is classified as "Applied Biological Science" in specialized course in Faculty of Engineering Cluster 3. In this class, theoretical bases on Feretemntation Technology experimantal trainig in Biotechnological experimental training course will be learned. Therefore, you should take Biotechnological experimental training course. And to comprehensively learn fermentation technology, it is highly recommended to take Fermentation Technology class.
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)	Program of Biotechnology （Knowledge and Understanding）・Acquisition of basic and advanced knowledge relating to biotechnology and life science. (Target/Lecture class)
Class Objectives /Class Outline	The aim is to learn basic knowledge on unit processes in modern fermentation technology. This class will give you theretical aspects on fermentation technology, while you will learn their practical aspects in Biotechnological experimental training course.
Class Schedule	lesson1 Introduction: What Do We Learn in Cultivation Technology? lesson2 Culture Media: Nutritional Requirements of Microorganisms lesson3 Microbial Energy Metabolism lesson4 Cultivation Methods I: Batch Culture lesson5 Batch Culture (Exercises) lesson6 Cultivation Methods II: Continuous Culture lesson7 Continuous Culture (Exercises) lesson8 Aeration and Agitation in Bioreactors lesson9 Aeration and Agitation (Exercises) lesson10 Cultivation Methods III: Fed-Batch Culture lesson11 Fed-Batch Culture (Exercises) lesson12 Sterilization Kinetics (Lecture and Exercises) lesson13 Strain Development lesson14 Amino Acid Fermentation lesson15 Modern Technologies for Controlling Microbial Growth
Text/Reference Books,etc.	P. F. Stanbury and A. Whitaker. Principles of Fermentation Technology. Pergamon Press Ltd.
PC or AV used in Class,etc.	Text
(More Details)
Learning techniques to be incorporated	Quizzes/ Quiz format, Post-class Report
Suggestions on Preparation and Review	1–3) Students will learn the theoretical foundations of microbial growth and energy metabolism, with reference to related subjects such as Biochemistry I and Fermentation Engineering. 4–12) Each class unit will include both lectures and exercises. For the exercises, problems will be assigned through Moodle in the previous class, and students are expected to complete them before the next class. Reports should also be submitted through Moodle. 4–7) The theoretical background and exercises related to batch culture experiments conducted in the student laboratory course (Cultivation Engineering Laboratory) will be covered. 13–15) Students will learn applied aspects of cultivation technology, including the principles of strain improvement used in modern fermentation production and practical approaches to microbial cultivation.
Requirements
Grading Method	The final exam: 80%, homeworks: 20%
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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