J1504160 Genomic Medicine

Hiroshima University Syllabus

Japanese

Academic Year 2026Year School/Graduate School School of Dentistry Program of Dentistry

Lecture Code J1504160 Subject Classification Specialized Education

Subject Name 基礎ゲノム医学

Subject Name
（Katakana）キソゲノムイガク

Subject Name in
English Genomic Medicine

Instructor FUJII MAKIKO,MARUYAMA FUMITO,SHUKUNAMI CHISA,SUEHIRO TOMOYA

Instructor
(Katakana) フジイ　マキコ,マルヤマ　フミト,シュクナミ　チサ,スエヒロ　トモヤ

Campus Kasumi Semester/Term 2nd-Year,  Second Semester,  4Term

Days, Periods, and Classrooms (4T) Tues5-8：DEN Large Lecture Rm

Lesson Style Lecture Lesson Style
(More Details) Face-to-face

Lecture and practice in terminal chamber

Credits 2.0 Class Hours/Week 4 Language of Instruction B : Japanese／English

Course Level 2 : Undergraduate Low-Intermediate

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 03 : Basic Biology

Eligible Students second grade

Keywords Human genome, medical genetics, personalized medicine, SNP, genome polymorphism, epigenetics, miRNA

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) This course serves as a foundational subject for next-generation medicine, preparing students to integrate advancing genomic information into future dental practice and research.
It focuses on three key areas:
1.Bridging Science and Clinic: Students will understand how genomic knowledge translates into disease mechanisms and innovative therapies through precision medicine.
2. Medical Literacy: By examining research trends and societal movements, students will master the essential ethical and practical knowledge of genomic medicine required for all modern healthcare professionals.
3. Future Readiness: As genomic data becomes standard in routine clinical settings, this course provides a critical step in cultivating the expertise needed to make accurate clinical judgments and provide scientifically sound explanations to patients.
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) Dentistry
（Knowledge and Understanding）
・Knowledge regarding basic and clinical dental medicine
・Knowledge of life sciences
（Comprehensive Abilities）
・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice

Class Objectives
/Class Outline This course provide a comprehensive study of human genomic medicine, from its biological foundations to cutting-edge clinical applications and the associated Ethical, Legal, and Social Issues (ELSI).
The first half of the course focuses on organizing genomic knowledge as a basis for understanding diseases and developing new therapies, while providing an overview of current research and social trends. The second half goes beyond mere information transfer, focusing on "cultivating ethical values" in handling genomic data. Specifically, students will explore delicate clinical scenarios, such as the strict management of genomic information and the disclosure of "incurable or difficult-to-treat diseases." Students will deeply consider how to respect the feelings of patients and their families and how to support their decision-making processes, both as healthcare professionals and as human beings.
【Course Objectives】
Systematic Understanding of Genomic Medicine: Accurately explain disease mechanisms and the principles of the latest genomic diagnostics and therapies based on fundamental human genome knowledge.
Strict Data Management Capabilities: Recognize that genomic information is the ultimate form of personal data and adopt an attitude of compliance with legal and ethical rules regarding its storage and handling.
Resolution of Ethical Dilemmas: For questions without a single correct answer—such as the disclosure of hereditary diseases with no established cure—derive a decision-making process that considers medical, psychological, and social impacts from the patient’s perspective.
Embodiment of Medical Ethics: Understand both the benefits of genomic data and the risks, such as discrimination or privacy violations, and act with a high standard of professional conduct as a leader in next-generation healthcare.

Class Schedule All the lectures are carried out along the textbook.

Lesson1, 2 Guidance, Living organism

Lessen 1.2 What is Genome?
Lessen 3.4 Genetics in disease
Lessen 5.6 epigenetics and gene expression
Lessen 7.8 precision medicine
Lessen 9.10  Biological informatics, literacy
Lessen 12.13.14.15  practice in terminal chamber
Lessen 15 examination

Text/Reference
Books,etc. Genome 4

PC or AV used in
Class,etc. Text, Handouts, Audio Materials, Visual Materials, moodle

(More Details) White/Black boards, LCD projector, personal PC in terminal chamber

Learning techniques to be incorporated Post-class Report

Suggestions on
Preparation and
Review The course will primarily use a textbook for lectures. Students are expected to read the relevant sections to deepen their understanding. Additionally, assignments will be submitted through Moodle for each lecture, and students should study the content thoroughly.

Requirements

Grading Method Attendance, submission of assignments, and a test score of 60 points or higher are required to earn credit for this course.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message We strongly recommend taking this class to understand new topics based on genetics, which are likely to increase in importance in the future medical field.

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2026Year	School/Graduate School	School of Dentistry Program of Dentistry
Lecture Code	J1504160	Subject Classification	Specialized Education
Subject Name	基礎ゲノム医学
Subject Name （Katakana）	キソゲノムイガク
Subject Name in English	Genomic Medicine
Instructor	FUJII MAKIKO,MARUYAMA FUMITO,SHUKUNAMI CHISA,SUEHIRO TOMOYA
Instructor (Katakana)	フジイ　マキコ,マルヤマ　フミト,シュクナミ　チサ,スエヒロ　トモヤ
Campus	Kasumi	Semester/Term	2nd-Year, Second Semester, 4Term
Days, Periods, and Classrooms	(4T) Tues5-8：DEN Large Lecture Rm
Lesson Style	Lecture	Lesson Style (More Details)	Face-to-face
Lecture and practice in terminal chamber
Credits	2.0	Class Hours/Week	4	Language of Instruction	B : Japanese／English
Course Level	2 : Undergraduate Low-Intermediate
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	03 : Basic Biology
Eligible Students	second grade
Keywords	Human genome, medical genetics, personalized medicine, SNP, genome polymorphism, epigenetics, miRNA
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)	This course serves as a foundational subject for next-generation medicine, preparing students to integrate advancing genomic information into future dental practice and research. It focuses on three key areas: 1.Bridging Science and Clinic: Students will understand how genomic knowledge translates into disease mechanisms and innovative therapies through precision medicine. 2. Medical Literacy: By examining research trends and societal movements, students will master the essential ethical and practical knowledge of genomic medicine required for all modern healthcare professionals. 3. Future Readiness: As genomic data becomes standard in routine clinical settings, this course provides a critical step in cultivating the expertise needed to make accurate clinical judgments and provide scientifically sound explanations to patients.
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)	Dentistry （Knowledge and Understanding）・Knowledge regarding basic and clinical dental medicine ・Knowledge of life sciences （Comprehensive Abilities）・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice
Class Objectives /Class Outline	This course provide a comprehensive study of human genomic medicine, from its biological foundations to cutting-edge clinical applications and the associated Ethical, Legal, and Social Issues (ELSI). The first half of the course focuses on organizing genomic knowledge as a basis for understanding diseases and developing new therapies, while providing an overview of current research and social trends. The second half goes beyond mere information transfer, focusing on "cultivating ethical values" in handling genomic data. Specifically, students will explore delicate clinical scenarios, such as the strict management of genomic information and the disclosure of "incurable or difficult-to-treat diseases." Students will deeply consider how to respect the feelings of patients and their families and how to support their decision-making processes, both as healthcare professionals and as human beings. 【Course Objectives】 Systematic Understanding of Genomic Medicine: Accurately explain disease mechanisms and the principles of the latest genomic diagnostics and therapies based on fundamental human genome knowledge. Strict Data Management Capabilities: Recognize that genomic information is the ultimate form of personal data and adopt an attitude of compliance with legal and ethical rules regarding its storage and handling. Resolution of Ethical Dilemmas: For questions without a single correct answer—such as the disclosure of hereditary diseases with no established cure—derive a decision-making process that considers medical, psychological, and social impacts from the patient’s perspective. Embodiment of Medical Ethics: Understand both the benefits of genomic data and the risks, such as discrimination or privacy violations, and act with a high standard of professional conduct as a leader in next-generation healthcare.
Class Schedule	All the lectures are carried out along the textbook. Lesson1, 2 Guidance, Living organism Lessen 1.2 What is Genome? Lessen 3.4 Genetics in disease Lessen 5.6 epigenetics and gene expression Lessen 7.8 precision medicine Lessen 9.10 Biological informatics, literacy Lessen 12.13.14.15 practice in terminal chamber Lessen 15 examination
Text/Reference Books,etc.	Genome 4
PC or AV used in Class,etc.	Text, Handouts, Audio Materials, Visual Materials, moodle
(More Details)	White/Black boards, LCD projector, personal PC in terminal chamber
Learning techniques to be incorporated	Post-class Report
Suggestions on Preparation and Review	The course will primarily use a textbook for lectures. Students are expected to read the relevant sections to deepen their understanding. Additionally, assignments will be submitted through Moodle for each lecture, and students should study the content thoroughly.
Requirements
Grading Method	Attendance, submission of assignments, and a test score of 60 points or higher are required to earn credit for this course.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message	We strongly recommend taking this class to understand new topics based on genetics, which are likely to increase in importance in the future medical field.
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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