Hiroshima University Syllabus

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Japanese
Academic Year 2025Year School/Graduate School School of Pharmaceutical Sciences Program of Pharmaceutical Sciences
Lecture Code I7013001 Subject Classification Specialized Education
Subject Name 生物薬剤学
Subject Name
(Katakana)
セイブツヤクザイガク
Subject Name in
English
Biopharmaceutics
Instructor UCHIDA YASUO
Instructor
(Katakana)
ウチダ ヤスオ
Campus Kasumi Semester/Term 2nd-Year,  Second Semester,  3Term
Days, Periods, and Classrooms (3T) Fri1-4:霞R304講義室
Lesson Style Lecture Lesson Style
(More Details)
Face-to-face, Online (on-demand)
Lecture,a chalk talk 
Credits 2.0 Class Hours/Week 4 Language of Instruction B : Japanese/English
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 03 : Pharmaceutical Sciences
Eligible Students 2nd-grade students
Keywords Absorption, Distribution, Metabolism, Excretion (ADME) 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students)
The third step: ADME 
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students)
Pharmaceutical Sciences
(Knowledge and Understanding)
・Knowledge and understanding about rational analyses of pharmacokinetics in order to to understand quantitatively madicinal effects or side effects. ●quality ⑤ ⑦
(Abilities and Skills)
・Abilities・skills of thinking ways of coping to reduce harmful effects(side effects) of madicine. ●quality ④

Medicinal Sciences
(Knowledge and Understanding)
・The knowledge relating to mutual reaction between chemical compounds including medicine and a human body
(Abilities and Skills)
・Development of knowledge relating to mutual reaction between chemical compounds including medicine and a human body (application) 
Class Objectives
/Class Outline
The course objective is to understand the process of absorption, distribution, metabolism and excretion. 
Class Schedule lesson1: Outline of biopharmaceutics(1) Handout(whole textbook)
lesson2: Outline of biopharmaceutics(2)  Handout(whole textbook)
lesson3: Membrane transport of drugs (1) P7-P26
lesson4: Membrane transport of drugs (2) P7-P26
lesson5: Intestinal absorption (1) P27-P64
lesson6: Intestinal absorption (2) P27-P64
lesson7: Protein binding (1) P69-P76
lesson8: Protein binding (2) P69-P76
lesson9: Distribution (1) P65-P69、P76-P91
lesson10: Distribution (2) P65-P69、P76-P91
lesson11: Metabolism (1) P92-P112
lesson12: Metabolism (2) P92-P112
lesson13: Excretion (1) P113-P141
lesson14: Excretion (2) P113-P141
lesson15: Excretion (3) P113-P141

small examination, main examinations 
Text/Reference
Books,etc.
パートナー薬剤学 改訂第4版 
PC or AV used in
Class,etc.
Text, Handouts, Microsoft Stream, moodle
(More Details) PowerPoint presentation, a chalk talk, prints, textbook 
Learning techniques to be incorporated Quizzes/ Quiz format
Suggestions on
Preparation and
Review
Please contact early if you have some questions. 
Requirements A calculator is required for exercises. 
Grading Method Grading will be based on the results of small exam (15 points) and main examinations (85 points). 60 points or more than 60 points in total are necessary to get a credit of this class. If it is less than 60 points, rescue examination will be held. In the rescue examination, 60 points or more than 60 points are necessary to get a credit of this class.
 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message Lectures are mainly conducted in Japanese and some in English. Lecture materials are written in both Japanese and English. 
Other C-1-3 (4)、C-6-1 (1)、D-4-1 (1)~(2)、D-4-1 (3)

This subject is closely related with the following subjects, and the relationship will be shown in class. Through its integrative learning, the students can understand the concept and positioning in pharmaceutical field.

C-1-3 (4):general chemistry, pharmaceutical physical chemistry, biological physical chemistry
C-6-1 (1):practice of cellular molecular biology, biochemistry V, biological physical chemistry, practice of biological chemistry
D-4-1 (1)~(2):pharmacology I, Pharmaceutical Health Science Ⅲ, practice of Pharmaceutical Health Science, practice of pharmaceutical science
D-4-1 (3):practice of pharmaceutical science
 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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