| Academic Year |
2024Year |
School/Graduate School |
Graduate School of Integrated Sciences for Life (Doctoral Course) |
| Lecture Code |
WI201100 |
Subject Classification |
Specialized Education |
| Subject Name |
ゲノム編集先端研究特論A |
Subject Name
（Katakana） |
ゲノムヘンシュウセンタンケンキュウトクロンA |
Subject Name in
English |
Trends of Genome Editing in Life Science |
| Instructor |
NOMURA WATARU,MATSUMOTO DAISUKE,SUGI TAKUMA |
Instructor
(Katakana) |
ノムラ ワタル,マツモト ダイスケ,スギ タクマ |
| Campus |
Across Campuses (videoconferencing, etc.) |
Semester/Term |
1st-Year, Second Semester, 3Term |
| Days, Periods, and Classrooms |
(3T) Tues11-12,Fri11-12：Online |
| Lesson Style |
Lecture |
Lesson Style
(More Details) |
|
| Online lectures using the Moodle system. Details will be emailed to students. |
| Credits |
2.0 |
Class Hours/Week |
|
Language of Instruction |
B
:
Japanese／English |
| Course Level |
7
:
Graduate Special Studies
|
| Course Area（Area） |
26
:
Biological and Life Sciences |
| Course Area（Discipline） |
03
:
Basic Biology |
| Eligible Students |
Doctor's students in the Frontier Development Program for Genome Editing |
| Keywords |
SDG_03, SDG_09 |
| Special Subject for Teacher Education |
|
Special Subject |
|
Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) | |
|---|
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) | |
|---|
Class Objectives
/Class Outline |
Teachures who are specialists of genome editing technology will give lectures on advanced technologies related to genome editing and explain their principles and application examples. Students will learn advanced technologies of genome editing including various CRISPR systems, transcription regulation, advanced genome editing using various effectors, CRISPR library screening, chromosome labeling, nucleic acid detection, recombinase technologies etc. |
| Class Schedule |
lesson1 : Introduction of this course (Wataru Nomura)
lesson2 : Base editing technology (Hiroshi Ochiai) (Note: the order of lectures may change)
lesson3 : Utilization of next-generation sequencer in genome editing research (I) (Hiroshi Ochiai)
lesson4 : Utilization of next-generation sequencer in genome editing research (II) (Hiroshi Ochiai)
lesson5 : Advanced tool development for TALEN and CRISPR (Daisuke Matsumoto)
lesson6 : Advanced gene knock-in technology in cultured cells (Daisuke Matsumoto)
lesson7 : Advanced technologies in gene knock-in in various animals and their applied research examples (Hiroshi Ochiai)
lesson8 : Transcriptional regulation and epigenome editing technologies (Wataru Nomura)
lesson9 : CRISPR library screening (Hiroshi Ochiai)
lesson10 : RNA editing technology using CRISPR (Hiroshi Ochiai)
lesson11 : Advanced technology of labeling specific genomic loci (Hiroshi Ochiai)
lesson12 : Chromosome reorganization technology using genome editing (Hiroshi Ochiai)
lesson13 : ZFN technology (Wataru Nomura)
lesson14 : Recombinase technology (Wataru Nomura)
lesson15 : Structural biology of genome editing (Takuma Sugi) |
Text/Reference
Books,etc. |
No particular textbook. |
PC or AV used in
Class,etc. |
|
| (More Details) |
Moodle system, handout |
| Learning techniques to be incorporated |
|
Suggestions on
Preparation and
Review |
Instructors will give instructions about preparation and review as needed. |
| Requirements |
|
| Grading Method |
The final grade is formed as a weighed sum of small exams mark and reports. |
| Practical Experience |
|
| Summary of Practical Experience and Class Contents based on it |
|
| Message |
|
| Other |
|
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. |