WH104003 Introduction to Disease Models

Hiroshima University Syllabus

Japanese

Academic Year 2024Year School/Graduate School Graduate School of Integrated Sciences for Life (Master's Course) Division of Integrated Sciences for Life Program of Biomedical Science

Lecture Code WH104003 Subject Classification Specialized Education

Subject Name 疾患モデル生物概論

Subject Name
（Katakana）シッカンモデルセイブツガイロン

Subject Name in
English Introduction to Disease Models

Instructor CHIHARA TAKAHIRO,OGINO HAJIME,IMAMURA TAKUYA,NAKAE SUSUMU,UENO MASARU,KIKUCHI YUTAKA,HAYASHI TOSHINORI,HOSOBA KOSUKE,MIZUNUMA MASAKI,YOSHIDA MASAYUKI,YANAKA NORIYUKI,UKENA KAZUYOSHI,ISHIHARA YASUHIRO,HONDA MIZUKI

Instructor
(Katakana) チハラ　タカヒロ,オギノ　ハジメ,イマムラ　タクヤ,ナカエ　ススム,ウエノ　マサル,キクチ　ユタカ,ハヤシ　トシノリ,ホソバ　コウスケ,ミズヌマ　マサキ,ヨシダ　マサユキ,ヤナカ　ノリユキ,ウケナ　カズヨシ,イシハラ　ヤスヒロ,ホンダ　ミズキ

Campus Higashi-Hiroshima Semester/Term 1st-Year, Second Semester, 3Term

Days, Periods, and Classrooms (3T) Tues1-2,Thur1-2：Online

Lesson Style Lecture Lesson Style
(More Details) 　

Lecturers who are actually conducting research using each model organism explain the features and application methods of each model organism. Because this lecture subject will be able to facilitate your own research, we recommend taking this lecture in the first year of master course. Each lecture will be provided via Microsoft Teams (either in on-demand or live online style). The viewing period for each session is one week. Please check moodle for details.

Credits 2.0 Class Hours/Week 　 Language of Instruction B : Japanese／English

Course Level 5 : Graduate Basic

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 04 : Life Sciences

Eligible Students Mainly first year students in master course

Keywords Biology, Model Organism, Disease, Biomedical Science, SDG_03

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students)

Class Objectives
/Class Outline Model organisms (cultured cells, yeast, nematode, fruit fly, amphibian, zebrafish, mouse, rat) are useful for putting the basic life science knowledge to the practical medical use. This lecture aims to learn the usefulness and limitations of each model organisms for biomedical sciences.

Class Schedule lesson1 Lecture Guidance (Takahiro Chihara)
lesson2 Single cell-level analyses towards the understanding of mammalian
brain development (Takuya Imamura)
lesson3 Mice as a lifestyle-related disease model (Noriyuki Yanaka)
lesson4 Establishment of disease model mice (Kosuke Hosoba)
lesson5 Mouse model for neurological disorders (Yasuhiro Ishihara)
lesson6 Mouse model for immune diseases (Susumu Nakae)
lesson7 Spatial omics analysis using human samples (Mizuki Honda)
lesson8 Rat for metabolic disease model (Kazuyoshi Ukena)
lesson9 in vitro disease models (Yutaka Kikuchi)
lesson10 Fishes for studying neural and behavioral disorders (Masayuki Yoshida)
lesson11 The use of pipid frogs for studying congenital diseases and organ regeneration (Hajime Ogino)
lesson12 Application of urodele amphibians to disease model (Toshinori Hayashi)
lesson13 C. elegans for aging studies (Masaki Mizunuma)
lesson14 Yeast as a Model Organism for Studying Cancer (Masaru Ueno)
lesson15 Drosophila as a disease model (Takahiro Chihara)

Text/Reference
Books,etc. The handouts will be provided in each lecture.

PC or AV used in
Class,etc. 　

(More Details) BulletinBoard system Bb9 via either your PC or SmartPhones

Learning techniques to be incorporated 　

Suggestions on
Preparation and
Review Details such as viewing methods will be explained in the guidance (first class). Instructors will provide instructions about preparation and review as needed.

Requirements

Grading Method The final grade will be based on a sum of small exams and reports.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2024Year	School/Graduate School	Graduate School of Integrated Sciences for Life (Master's Course) Division of Integrated Sciences for Life Program of Biomedical Science
Lecture Code	WH104003	Subject Classification	Specialized Education
Subject Name	疾患モデル生物概論
Subject Name （Katakana）	シッカンモデルセイブツガイロン
Subject Name in English	Introduction to Disease Models
Instructor	CHIHARA TAKAHIRO,OGINO HAJIME,IMAMURA TAKUYA,NAKAE SUSUMU,UENO MASARU,KIKUCHI YUTAKA,HAYASHI TOSHINORI,HOSOBA KOSUKE,MIZUNUMA MASAKI,YOSHIDA MASAYUKI,YANAKA NORIYUKI,UKENA KAZUYOSHI,ISHIHARA YASUHIRO,HONDA MIZUKI
Instructor (Katakana)	チハラ　タカヒロ,オギノ　ハジメ,イマムラ　タクヤ,ナカエ　ススム,ウエノ　マサル,キクチ　ユタカ,ハヤシ　トシノリ,ホソバ　コウスケ,ミズヌマ　マサキ,ヨシダ　マサユキ,ヤナカ　ノリユキ,ウケナ　カズヨシ,イシハラ　ヤスヒロ,ホンダ　ミズキ
Campus	Higashi-Hiroshima	Semester/Term	1st-Year, Second Semester, 3Term
Days, Periods, and Classrooms	(3T) Tues1-2,Thur1-2：Online
Lesson Style	Lecture	Lesson Style (More Details)
Lecturers who are actually conducting research using each model organism explain the features and application methods of each model organism. Because this lecture subject will be able to facilitate your own research, we recommend taking this lecture in the first year of master course. Each lecture will be provided via Microsoft Teams (either in on-demand or live online style). The viewing period for each session is one week. Please check moodle for details.
Credits	2.0	Class Hours/Week		Language of Instruction	B : Japanese／English
Course Level	5 : Graduate Basic
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	04 : Life Sciences
Eligible Students	Mainly first year students in master course
Keywords	Biology, Model Organism, Disease, Biomedical Science, SDG_03
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)
Class Objectives /Class Outline	Model organisms (cultured cells, yeast, nematode, fruit fly, amphibian, zebrafish, mouse, rat) are useful for putting the basic life science knowledge to the practical medical use. This lecture aims to learn the usefulness and limitations of each model organisms for biomedical sciences.
Class Schedule	lesson1 Lecture Guidance (Takahiro Chihara) lesson2 Single cell-level analyses towards the understanding of mammalian brain development (Takuya Imamura) lesson3 Mice as a lifestyle-related disease model (Noriyuki Yanaka) lesson4 Establishment of disease model mice (Kosuke Hosoba) lesson5 Mouse model for neurological disorders (Yasuhiro Ishihara) lesson6 Mouse model for immune diseases (Susumu Nakae) lesson7 Spatial omics analysis using human samples (Mizuki Honda) lesson8 Rat for metabolic disease model (Kazuyoshi Ukena) lesson9 in vitro disease models (Yutaka Kikuchi) lesson10 Fishes for studying neural and behavioral disorders (Masayuki Yoshida) lesson11 The use of pipid frogs for studying congenital diseases and organ regeneration (Hajime Ogino) lesson12 Application of urodele amphibians to disease model (Toshinori Hayashi) lesson13 C. elegans for aging studies (Masaki Mizunuma) lesson14 Yeast as a Model Organism for Studying Cancer (Masaru Ueno) lesson15 Drosophila as a disease model (Takahiro Chihara)
Text/Reference Books,etc.	The handouts will be provided in each lecture.
PC or AV used in Class,etc.
(More Details)	BulletinBoard system Bb9 via either your PC or SmartPhones
Learning techniques to be incorporated
Suggestions on Preparation and Review	Details such as viewing methods will be explained in the guidance (first class). Instructors will provide instructions about preparation and review as needed.
Requirements
Grading Method	The final grade will be based on a sum of small exams and reports.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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