WG123001 Molecular Biophysics

Hiroshima University Syllabus

Japanese

Academic Year 2024Year School/Graduate School Graduate School of Integrated Sciences for Life (Master's Course) Division of Integrated Sciences for Life Program of Mathematical and Life Sciences

Lecture Code WG123001 Subject Classification Specialized Education

Subject Name 分子生物物理学

Subject Name
（Katakana）ブンシセイブツブツリガク

Subject Name in
English Molecular Biophysics

Instructor TATE SHINICHI,YASUDA KYOTA,OOMAE EIJI,KATAYANAGI KATSUO

Instructor
(Katakana) タテ　シンイチ,ヤスダ　キョウタ,オオマエ　エイジ,カタヤナギ　カツオ

Campus Higashi-Hiroshima Semester/Term 1st-Year,  First Semester,  1Term

Days, Periods, and Classrooms (1T) Tues1-2,Fri1-2：SCI B305

Lesson Style Lecture Lesson Style
(More Details) 　

In this lecture course, we are going to teach you the basic experimental approaches to quantitatively understand the events in life, with emphasis on protein researches. Advancements that emerged over recent years will be delivered to awaken your interest in topical questions. All lectures are presented in English.

Credits 2.0 Class Hours/Week 　 Language of Instruction E : English

Course Level 5 : Graduate Basic

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 03 : Basic Biology

Eligible Students Master course students

Keywords biophysics; cell; bio-molecules; instrumentation and measurement

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) The course aims to give you the basic ideas how to obtain quantitative insights into how proteins work in vitro and in vivo, which constitute the principal issues in life science. You may also learn how to combine your basic knowledge together to grasp the various aspects of proteins.
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students)

Class Objectives
/Class Outline Students are expected to gain the basic concepts in the experimental approaches required in biophysics. They will become familiar with the interdisciplinary research flavor through the lectures.

Class Schedule lesson1: Introduction to protein chemistry: Protein structure-function relationship
lesson2: NMR(1): NMR techniques to solve the solution structure of protein
lesson3: NMR(2): NMR techniques to solve the protein structural dynamics
lesson4: X-ray(1) Crystallography of single crystal

lesson5: X-ray(2) Treatment of Symmetry　　　
lesson6: X-ray(3) Patterson Function
lesson7: X-ray(4) Anomalous Dispersion
lesson8: Enzymology(1): Thermodynamic analysis of structural stability of enzymes (1)
lesson9: Enzymology(2): Thermodynamic analysis of structural stability of enzymes (2)
lesson10: Enzymology(3): Thermodynamic and kinetic analyses of enzyme functions (1)
lesson11: Enzymology(4):Thermodynamic and kinetic analyses of enzyme functions (2)
lesson12: Cell biology experiments(1)
lesson13: Cell biology experiments(2)
lesson14: Cell biology experiments(3)
lesson15: Cell biology experiments(4)

The students are required to submit the reports on the relating subjects the lectures, at the end of the course.

1-3: Tate, 4-7: Katayanagi, 8-11: Ohmae, 12-15: Yasuda

Text/Reference
Books,etc. Handouts.

PC or AV used in
Class,etc. 　

(More Details) PC projector and handouts in need

Learning techniques to be incorporated 　

Suggestions on
Preparation and
Review Grasp the essence in the classes. Think deeply in solving the problems given in the final of the lecture course.

Requirements

Grading Method The reports on the problems given at the final of the course will be evaluated, besides the engagement in the class discussion.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message Active discussion in the classes. Questions in a class are recommended.

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2024Year	School/Graduate School	Graduate School of Integrated Sciences for Life (Master's Course) Division of Integrated Sciences for Life Program of Mathematical and Life Sciences
Lecture Code	WG123001	Subject Classification	Specialized Education
Subject Name	分子生物物理学
Subject Name （Katakana）	ブンシセイブツブツリガク
Subject Name in English	Molecular Biophysics
Instructor	TATE SHINICHI,YASUDA KYOTA,OOMAE EIJI,KATAYANAGI KATSUO
Instructor (Katakana)	タテ　シンイチ,ヤスダ　キョウタ,オオマエ　エイジ,カタヤナギ　カツオ
Campus	Higashi-Hiroshima	Semester/Term	1st-Year, First Semester, 1Term
Days, Periods, and Classrooms	(1T) Tues1-2,Fri1-2：SCI B305
Lesson Style	Lecture	Lesson Style (More Details)
In this lecture course, we are going to teach you the basic experimental approaches to quantitatively understand the events in life, with emphasis on protein researches. Advancements that emerged over recent years will be delivered to awaken your interest in topical questions. All lectures are presented in English.
Credits	2.0	Class Hours/Week		Language of Instruction	E : English
Course Level	5 : Graduate Basic
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	03 : Basic Biology
Eligible Students	Master course students
Keywords	biophysics; cell; bio-molecules; instrumentation and measurement
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)	The course aims to give you the basic ideas how to obtain quantitative insights into how proteins work in vitro and in vivo, which constitute the principal issues in life science. You may also learn how to combine your basic knowledge together to grasp the various aspects of proteins.
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)
Class Objectives /Class Outline	Students are expected to gain the basic concepts in the experimental approaches required in biophysics. They will become familiar with the interdisciplinary research flavor through the lectures.
Class Schedule	lesson1: Introduction to protein chemistry: Protein structure-function relationship lesson2: NMR(1): NMR techniques to solve the solution structure of protein lesson3: NMR(2): NMR techniques to solve the protein structural dynamics lesson4: X-ray(1) Crystallography of single crystal lesson5: X-ray(2) Treatment of Symmetry　　　 lesson6: X-ray(3) Patterson Function lesson7: X-ray(4) Anomalous Dispersion lesson8: Enzymology(1): Thermodynamic analysis of structural stability of enzymes (1) lesson9: Enzymology(2): Thermodynamic analysis of structural stability of enzymes (2) lesson10: Enzymology(3): Thermodynamic and kinetic analyses of enzyme functions (1) lesson11: Enzymology(4):Thermodynamic and kinetic analyses of enzyme functions (2) lesson12: Cell biology experiments(1) lesson13: Cell biology experiments(2) lesson14: Cell biology experiments(3) lesson15: Cell biology experiments(4) The students are required to submit the reports on the relating subjects the lectures, at the end of the course. 1-3: Tate, 4-7: Katayanagi, 8-11: Ohmae, 12-15: Yasuda
Text/Reference Books,etc.	Handouts.
PC or AV used in Class,etc.
(More Details)	PC projector and handouts in need
Learning techniques to be incorporated
Suggestions on Preparation and Review	Grasp the essence in the classes. Think deeply in solving the problems given in the final of the lecture course.
Requirements
Grading Method	The reports on the problems given at the final of the course will be evaluated, besides the engagement in the class discussion.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message	Active discussion in the classes. Questions in a class are recommended.
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

Back to syllabus main page