| Academic Year |
2024Year |
School/Graduate School |
Graduate School of Biomedical and Health Sciences (Master’s Course) |
| Lecture Code |
TB804001 |
Subject Classification |
Specialized Education |
| Subject Name |
核酸分析化学特論 |
Subject Name
（Katakana） |
カクサンブンセキカガクトクロン |
Subject Name in
English |
Lecture on Nucleic Acids Biochemistry |
| Instructor |
KAMIYA HIROYUKI |
Instructor
(Katakana) |
カミヤ ヒロユキ |
| Campus |
Kasumi |
Semester/Term |
1st-Year, First Semester, First Semester |
| Days, Periods, and Classrooms |
(1st) Thur3-4：霞R203講義室 |
| Lesson Style |
Lecture |
Lesson Style
(More Details) |
|
| Lecture |
| Credits |
2.0 |
Class Hours/Week |
|
Language of Instruction |
B
:
Japanese／English |
| Course Level |
6
:
Graduate Advanced
|
| Course Area（Area） |
27
:
Health Sciences |
| Course Area（Discipline） |
03
:
Pharmaceutical Sciences |
| Eligible Students |
|
| Keywords |
mutation, cancer, DNA replication, DNA damage, DNA repair, nucleic acid medicine, gene therapy |
| Special Subject for Teacher Education |
|
Special Subject |
|
Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) | |
|---|
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) | |
|---|
Class Objectives
/Class Outline |
Students can understand structures and properties of nucleic acids, biological significance of DNA damage, and medical applications of nucleic acids. |
| Class Schedule |
lesson 1: Structures and properties of nucleic acids
lesson 2: Diseases caused by mutations
lesson 3: Errors during DNA replication
lesson 4: Discussion (1)
lesson 5: Mutagenesis caused by DNA damage (1)
lesson 6: Mutagenesis caused by DNA damage (2)
lesson 7: DNA repair (1)
lesson 8: DNA repair (2)
lesson 9: Chemical carcinogenesis
lesson 10: Discussion (2)
lesson 11: Anticancer drugs (nucleoside analogs)
lesson 12: Chemical synthesis of nucleic acids and Nucleic acid medicines (1)
lesson 13: Nucleic acid medicines (2)
lesson 14: Gene therapy
lesson 15: Discussion (3)
mini-reports and final report
This class is conducted to read current research papers concerning students' research theme. |
Text/Reference
Books,etc. |
No text book |
PC or AV used in
Class,etc. |
|
| (More Details) |
Slides |
| Learning techniques to be incorporated |
|
Suggestions on
Preparation and
Review |
lesson 1: To understand structures and properties of nucleic acids
lesson 2: To understand diseases caused by mutations
lesson 3: To understand fidelity of DNA replication
lessons 5 and 6: To understand mechanisms of mutagenesis caused by DNA damage
lessons 7 and 8: To understand mechanisms of DNA repair and mutation suppression
lesson 9: To understand mechanisms of chemical carcinogenesis
lesson 11: To understand mechanisms of action for anticancer drugs
lesson 12: To understand chemical synthesis of nucleic acids
lessons 12 and 13: To understand mechanisms of action for nucleic acid medicines
lesson 14: To understand gene therapy
|
| Requirements |
none in particular |
| Grading Method |
mini-report 15%, ardency 15%, final report 70% |
| Practical Experience |
|
| Summary of Practical Experience and Class Contents based on it |
|
| Message |
Talk in Japanese, slides and handouts in both Japanese and English |
| Other |
|
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. |