63300301 Ethics and regulations in natural science research

Hiroshima University Syllabus

Japanese

Academic Year 2024Year School/Graduate School Liberal Arts Education Program

Lecture Code 63300301 Subject Classification Area Courses

Subject Name 自然科学研究の倫理と法令

Subject Name
（Katakana）シゼンカガクケンキユウノリンリトホウレイ

Subject Name in
English Ethics and regulations in natural science research

Instructor KITAMURA KENJI,TANAKA NOBUKAZU,FURUMIZU CHIHIRO,UMEO KAZUNORI,NAKASHIMA SATORU,INADA KUNINOBU,NOBUKIYO ASAKO,MATSUSHIMA AKIHITO,SOTOMARU YUSUKE

Instructor
(Katakana) キタムラ　ケンジ,タナカ　ノブカズ,フルミズ　チヒロ,ウメオ　カズノリ,ナカシマ　サトル,イナダ　クニノブ,ノブキヨ　アサコ,マツシマ　アキヒト,ソトマル　ユウスケ

Campus Higashi-Hiroshima Semester/Term 1st-Year, First Semester, 1Term

Days, Periods, and Classrooms (1T) Mon5-8：IAS K206

Lesson Style Lecture Lesson Style
(More Details) 　

Face-to-face lecture.
If case of online lecture, inform in advance.

Credits 2.0 Class Hours/Week 　 Language of Instruction J : Japanese

Course Level 1 : Undergraduate Introductory

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 04 : Life Sciences

Eligible Students Undergraduate (first and more year) students

Keywords SDG_3, SDG_14, SDG_15, Safe management, Compliance, Biodiversity, Living modified organisms, Genetic resource, Genome editing, Animal Experiment, Animal welfare, Clone, iPS/ES, High pressure gas, Cryogen, Radiation effect, Radioisotope, Application of radiation, Environmental radioactivity, Nuclear accident

Special Subject for Teacher Education 　 Special Subject 　

Class Status within
Liberal Arts Education Area Courses（Courses in Natural Sciences)　Category：Biology
Expected Outcome In this lecture, students will learn basic and fundamental natural science ethics, related laws and regulations, and recent topics that they should know before starting actual natural scientific research at the university laboratory.

Class Objectives
/Class Outline [Objective] Modern natural science has developed rapidly and research in universities is in a position to lead its development. However, with the rapid progress of natural science, the sense of ethics that should be originally thought is diluted. Under such circumstances, since there is a possibility of misjudging the direction of natural science, it is necessary to regulate by law in order to deter it. In other words, it is important that the progress of natural scientific research is regulated so as not to deviate from the conservation of the natural environment and the maintenance of a safe human society, with awareness of SDGs. This class aims to understand the importance of compliance in the research and experiment of natural science.
[Outline] Faculty members engaged in radiation experiments, low temperature experiments, genetic experiments, and animal experiments at Integrated Experimental Support / Research Division in the Natural Science Center for Basic Research and Development will explain the ethics and laws on research and experiments in their respective fields in an easy-to-understand manner. The sense of compliance of students involved in natural science research will be fostered.
In this class, we divide the whole into four units of radiation experiments, cryogenic experiments, genetic experiments and animal experiments, and conduct related classes two to four lessons in each. Each person in charge is as follows;
1) Radiation experiment: Satoru Nakashima, Kuninobu Inada, and Akihito Matsushima
2) Cryogenic experiment: Kazunori Umeo
3) Genetic experiment: Nobukazu Tanaka, Kenji Kitamura, and Chihiro Furumizu
4) Animal experiment: Yusuke Sotomaru and Asako Nobukiyo

Class Schedule lesson1 Outline of this lecture: What is ethics and compliance in natural science researches? (Sotomaru)
lesson2 Radiation use and radiation regulation. (Nakashima)
lesson3 RI act and ordinances concerned. (Nakashima)
lesson4 Safety Utilization of Radiation for Life Science. (Inada)
lesson5 Environmental radiation (including Fukushima Nuclear Plant Accident). (Matsushima)
lesson6 Handling and Lows of high pressure gases. (Umeo)
lesson7 Handling and Lows of cryogens. (Umeo)
lesson8 Biodiversity and conservation of the natural environment. (Tanaka)
lesson9 Pathogenic microorganisms and living modified organisms. (Tanaka)
lesson10 Nagoya Protocol and ABS. (Kitamura)
lesson11 Digital sequence information and synthetic biology. (Kitamura)
lesson12 Genome editing and gene drive. (Furumizu)
lesson13 Ethics and laws related to animal experiments. (Sotomaru)
lesson14 Criteria for advanced animal experiments. (Sotomaru)
lesson15 Welfare of laboratory animals. (Nobukiyo)

Mini-test using Moodle after each lesson.
Final examination (final report)

Text/Reference
Books,etc. Not specified.

PC or AV used in
Class,etc. 　

(More Details)

Learning techniques to be incorporated 　

Suggestions on
Preparation and
Review lesson1：Understand the ethics and compliance in natural science researches.
lesson2：Understand the studies using radiation and the influence of radiation on human body.
lesson3：Understand the safety for radiation user and the public.
lesson4：Understand the safety utilization of radiation for life science.
lesson5：Understand the environmental radiation including artificial radiation spewing from nuclear power plant accident.
lesson6：Understand how to handle the high pressure gases and containers (bomb) and related lows.
lesson7：Understand how to handle cryogens (liquid nitrogen and helium) and related lows.
lesson8：Understand the maintenance of biodiversity important for conserving natural environment.
lesson9：Understand the attention to pathogenic microorganisms and the safety management of genetically modified organisms.
lesson10：Understand the concepts of Nagoya protocol and ABS for utilization of oversea genetic materials in biochemical studies.
lesson11：Understand the problem for utilizing gene sequence database information for genetic modification of living organisms (synthetic biology).
lesson12：Understand the impact of latest technologies, genome editing and gene drive, on the environment.
lesson13：Understand ethics and compliance with laws and regulations in animal experiments.
lesson14：Understand the norms of advanced animal experiments such as cloning and stem cells research.
lesson15：Understand the necessity of animal welfare for laboratory animals in animal experiments.

Requirements Although there are no particular attention and conditions for taking courses in this class, students who are planning to conduct research in the field of natural sciences, such as life sciences, are desirable.

Grading Method We evaluate at 100 points with about 50 points for each quiz and about 50 points for a final examination (final report).

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message Nothing

Other All lectures will be made by Japanese language only. International students must be fluent in Japanese to understand lecture content.

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2024Year	School/Graduate School	Liberal Arts Education Program
Lecture Code	63300301	Subject Classification	Area Courses
Subject Name	自然科学研究の倫理と法令
Subject Name （Katakana）	シゼンカガクケンキユウノリンリトホウレイ
Subject Name in English	Ethics and regulations in natural science research
Instructor	KITAMURA KENJI,TANAKA NOBUKAZU,FURUMIZU CHIHIRO,UMEO KAZUNORI,NAKASHIMA SATORU,INADA KUNINOBU,NOBUKIYO ASAKO,MATSUSHIMA AKIHITO,SOTOMARU YUSUKE
Instructor (Katakana)	キタムラ　ケンジ,タナカ　ノブカズ,フルミズ　チヒロ,ウメオ　カズノリ,ナカシマ　サトル,イナダ　クニノブ,ノブキヨ　アサコ,マツシマ　アキヒト,ソトマル　ユウスケ
Campus	Higashi-Hiroshima	Semester/Term	1st-Year, First Semester, 1Term
Days, Periods, and Classrooms	(1T) Mon5-8：IAS K206
Lesson Style	Lecture	Lesson Style (More Details)
Face-to-face lecture. If case of online lecture, inform in advance.
Credits	2.0	Class Hours/Week		Language of Instruction	J : Japanese
Course Level	1 : Undergraduate Introductory
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	04 : Life Sciences
Eligible Students	Undergraduate (first and more year) students
Keywords	SDG_3, SDG_14, SDG_15, Safe management, Compliance, Biodiversity, Living modified organisms, Genetic resource, Genome editing, Animal Experiment, Animal welfare, Clone, iPS/ES, High pressure gas, Cryogen, Radiation effect, Radioisotope, Application of radiation, Environmental radioactivity, Nuclear accident
Special Subject for Teacher Education		Special Subject
Class Status within Liberal Arts Education	Area Courses（Courses in Natural Sciences)　Category：Biology
Expected Outcome	In this lecture, students will learn basic and fundamental natural science ethics, related laws and regulations, and recent topics that they should know before starting actual natural scientific research at the university laboratory.
Class Objectives /Class Outline	[Objective] Modern natural science has developed rapidly and research in universities is in a position to lead its development. However, with the rapid progress of natural science, the sense of ethics that should be originally thought is diluted. Under such circumstances, since there is a possibility of misjudging the direction of natural science, it is necessary to regulate by law in order to deter it. In other words, it is important that the progress of natural scientific research is regulated so as not to deviate from the conservation of the natural environment and the maintenance of a safe human society, with awareness of SDGs. This class aims to understand the importance of compliance in the research and experiment of natural science. [Outline] Faculty members engaged in radiation experiments, low temperature experiments, genetic experiments, and animal experiments at Integrated Experimental Support / Research Division in the Natural Science Center for Basic Research and Development will explain the ethics and laws on research and experiments in their respective fields in an easy-to-understand manner. The sense of compliance of students involved in natural science research will be fostered. In this class, we divide the whole into four units of radiation experiments, cryogenic experiments, genetic experiments and animal experiments, and conduct related classes two to four lessons in each. Each person in charge is as follows; 1) Radiation experiment: Satoru Nakashima, Kuninobu Inada, and Akihito Matsushima 2) Cryogenic experiment: Kazunori Umeo 3) Genetic experiment: Nobukazu Tanaka, Kenji Kitamura, and Chihiro Furumizu 4) Animal experiment: Yusuke Sotomaru and Asako Nobukiyo
Class Schedule	lesson1 Outline of this lecture: What is ethics and compliance in natural science researches? (Sotomaru) lesson2 Radiation use and radiation regulation. (Nakashima) lesson3 RI act and ordinances concerned. (Nakashima) lesson4 Safety Utilization of Radiation for Life Science. (Inada) lesson5 Environmental radiation (including Fukushima Nuclear Plant Accident). (Matsushima) lesson6 Handling and Lows of high pressure gases. (Umeo) lesson7 Handling and Lows of cryogens. (Umeo) lesson8 Biodiversity and conservation of the natural environment. (Tanaka) lesson9 Pathogenic microorganisms and living modified organisms. (Tanaka) lesson10 Nagoya Protocol and ABS. (Kitamura) lesson11 Digital sequence information and synthetic biology. (Kitamura) lesson12 Genome editing and gene drive. (Furumizu) lesson13 Ethics and laws related to animal experiments. (Sotomaru) lesson14 Criteria for advanced animal experiments. (Sotomaru) lesson15 Welfare of laboratory animals. (Nobukiyo) Mini-test using Moodle after each lesson. Final examination (final report)
Text/Reference Books,etc.	Not specified.
PC or AV used in Class,etc.
(More Details)
Learning techniques to be incorporated
Suggestions on Preparation and Review	lesson1：Understand the ethics and compliance in natural science researches. lesson2：Understand the studies using radiation and the influence of radiation on human body. lesson3：Understand the safety for radiation user and the public. lesson4：Understand the safety utilization of radiation for life science. lesson5：Understand the environmental radiation including artificial radiation spewing from nuclear power plant accident. lesson6：Understand how to handle the high pressure gases and containers (bomb) and related lows. lesson7：Understand how to handle cryogens (liquid nitrogen and helium) and related lows. lesson8：Understand the maintenance of biodiversity important for conserving natural environment. lesson9：Understand the attention to pathogenic microorganisms and the safety management of genetically modified organisms. lesson10：Understand the concepts of Nagoya protocol and ABS for utilization of oversea genetic materials in biochemical studies. lesson11：Understand the problem for utilizing gene sequence database information for genetic modification of living organisms (synthetic biology). lesson12：Understand the impact of latest technologies, genome editing and gene drive, on the environment. lesson13：Understand ethics and compliance with laws and regulations in animal experiments. lesson14：Understand the norms of advanced animal experiments such as cloning and stem cells research. lesson15：Understand the necessity of animal welfare for laboratory animals in animal experiments.
Requirements	Although there are no particular attention and conditions for taking courses in this class, students who are planning to conduct research in the field of natural sciences, such as life sciences, are desirable.
Grading Method	We evaluate at 100 points with about 50 points for each quiz and about 50 points for a final examination (final report).
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message	Nothing
Other	All lectures will be made by Japanese language only. International students must be fluent in Japanese to understand lecture content.
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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