10000208 Advanced Seminar（Introduction of Genome Editing?How can we rewrite our genome??）

Hiroshima University Syllabus

Japanese

Academic Year 2024Year School/Graduate School Liberal Arts Education Program

Lecture Code 10000208 Subject Classification Advanced Seminar

Subject Name 展開ゼミ（ゲノム編集入門～実際のところ遺伝子を書き換えるってどんな感じなの？～）

Subject Name
（Katakana）テンカイゼミ（ゲノムヘンシュウニュウモンジッサイノトコロイデンシヲカキカエルッテドンナカンジナノ？）

Subject Name in
English Advanced Seminar（Introduction of Genome Editing?How can we rewrite our genome??）

Instructor MATSUMOTO DAISUKE

Instructor
(Katakana) マツモト　ダイスケ

Campus Kasumi Semester/Term 1st-Year, Second Semester, Intensive

Days, Periods, and Classrooms (Int) Inte：See Momiji Website for the detail.(Kasumi Campus)

Lesson Style Seminar Lesson Style
(More Details) 　

Experiments、Discussion、Presentation

Credits 1.0 Class Hours/Week 　 Language of Instruction B : Japanese／English

Course Level 1 : Undergraduate Introductory

Course Area（Area） 21 : Fundamental Competencies for Working Persons

Course Area（Discipline） 01 : Introductory Seminar for First-Year Students

Eligible Students All students in Hiroshima University

Keywords Genome editing, Creating idea, Problem-solving, Presentation

Special Subject for Teacher Education 　 Special Subject 　

Class Status within
Liberal Arts Education The "Advanced Seminar" will be held to give students opportunities to practically utilize their comprehensive knowledge to create new value and solve problems in society, based on their learning in the "Introductory Seminar for First-Year Students". It is designed for students to cultivate problem-finding and problem-solving skills through the study and discussion of cutting-edge topics and hands-on learning in small classes that transcend school and grade boundaries, and to develop challenge, presentation, and leadership skills.
Expected Outcome In combination with the "Introduction to University Education" and the "Introductory Seminar for First-Year Students", students are expected to:
1. Form an independent learning attitude
2. Improve their problem-finding and problem-solving skills
3. Improve their logical and critical thinking skills
4. Improve their reading comprehension, expression, presentation, and discussion skills
5. Improve their communication and leadership skills

Class Objectives
/Class Outline Through the subject of genome editing technology, which has been attracting attention in recent years, we will discuss how science and technology should be implemented in society and how to deal with the risks involved, transcending the boundaries between faculties, in order to build a bridge to subsequent specialized education.
While implementing genome editing using CRISPR-Cas9, we will discuss ideas for social implementation of genome editing and solutions to ethical issues. Specifically, while performing gene editing targeting green fluorescent protein, (1) the class instructor will explain about genome editing, (2) the class instructor will present actual social issues through his/her acquaintances, and (3) all participants will discuss the proposed solutions using genome editing for the issues raised. Students will select a theme related to the content of the discussion or a topic of personal interest, and write a report on it together with the results of their study afterwards. A part of the report will be compiled into a presentation of about 10 minutes.

Class Schedule lesson1 Basic lecture on genome editing, overview of experiments, genome editing experiments using cells (transfection), in vitro cleavage experiments
lesson3 Lecture on creativity by an external lecturer, listening to a presentation on an issue in a industry, group work to generate ideas for the issue
lesson3 Preliminary research and preparation of presentation materials (group work) to realize the idea
lesson4 Presentation of problem-solving ideas (group presentations)
lesson5 Genome editing experiment using cells (observation of results), discussion of results
lesson6 Discussion on ethical issues in social implementation of genome editing
lesson7 Research on genome editing topics of personal interest and preparation of presentation materials
lesson8 Plenary discussion (individual presentations)

Text/Reference
Books,etc. For the first, fourth, eleventh and twelfth lessons, we will use slides created by us as course materials. (The slides will be distributed via the online learning system "moodle," so please download them to your own laptop prior to the class.)

PC or AV used in
Class,etc. 　

(More Details)

Learning techniques to be incorporated 　

Suggestions on
Preparation and
Review Please read through the downloaded textbook in advance before taking the course or watching the class videos.

Requirements ・Due to space limitations, the maximum number of participants will be limited to six. If there are too many applicants, we will ask them to submit a 200-word explanation of why they wish to take the course, and the six applicants will be selected by drawing lots.

・The lecture will be held from the second to the fourth week of September (specific dates will be decided together with the participants at the orientation in December).

・The schedule will be decided together with the students at the orientation session (Teams) in January.

・Students are required to take out "Accident Insurance for Student Education and Research" in case of unforeseen circumstances during class hours or while returning home.

Grading Method (1) Active participation in lectures
(2) Submission of reports
(3) Evaluation of presentations in plenary discussions (evaluation is also conducted within the participants)
Evaluation will be on a pass/fail basis only, and will not be on a 5-step evaluation.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2024Year	School/Graduate School	Liberal Arts Education Program
Lecture Code	10000208	Subject Classification	Advanced Seminar
Subject Name	展開ゼミ（ゲノム編集入門～実際のところ遺伝子を書き換えるってどんな感じなの？～）
Subject Name （Katakana）	テンカイゼミ（ゲノムヘンシュウニュウモンジッサイノトコロイデンシヲカキカエルッテドンナカンジナノ？）
Subject Name in English	Advanced Seminar（Introduction of Genome Editing?How can we rewrite our genome??）
Instructor	MATSUMOTO DAISUKE
Instructor (Katakana)	マツモト　ダイスケ
Campus	Kasumi	Semester/Term	1st-Year, Second Semester, Intensive
Days, Periods, and Classrooms	(Int) Inte：See Momiji Website for the detail.(Kasumi Campus)
Lesson Style	Seminar	Lesson Style (More Details)
Experiments、Discussion、Presentation
Credits	1.0	Class Hours/Week		Language of Instruction	B : Japanese／English
Course Level	1 : Undergraduate Introductory
Course Area（Area）	21 : Fundamental Competencies for Working Persons
Course Area（Discipline）	01 : Introductory Seminar for First-Year Students
Eligible Students	All students in Hiroshima University
Keywords	Genome editing, Creating idea, Problem-solving, Presentation
Special Subject for Teacher Education		Special Subject
Class Status within Liberal Arts Education	The "Advanced Seminar" will be held to give students opportunities to practically utilize their comprehensive knowledge to create new value and solve problems in society, based on their learning in the "Introductory Seminar for First-Year Students". It is designed for students to cultivate problem-finding and problem-solving skills through the study and discussion of cutting-edge topics and hands-on learning in small classes that transcend school and grade boundaries, and to develop challenge, presentation, and leadership skills.
Expected Outcome	In combination with the "Introduction to University Education" and the "Introductory Seminar for First-Year Students", students are expected to: 1. Form an independent learning attitude 2. Improve their problem-finding and problem-solving skills 3. Improve their logical and critical thinking skills 4. Improve their reading comprehension, expression, presentation, and discussion skills 5. Improve their communication and leadership skills
Class Objectives /Class Outline	Through the subject of genome editing technology, which has been attracting attention in recent years, we will discuss how science and technology should be implemented in society and how to deal with the risks involved, transcending the boundaries between faculties, in order to build a bridge to subsequent specialized education. While implementing genome editing using CRISPR-Cas9, we will discuss ideas for social implementation of genome editing and solutions to ethical issues. Specifically, while performing gene editing targeting green fluorescent protein, (1) the class instructor will explain about genome editing, (2) the class instructor will present actual social issues through his/her acquaintances, and (3) all participants will discuss the proposed solutions using genome editing for the issues raised. Students will select a theme related to the content of the discussion or a topic of personal interest, and write a report on it together with the results of their study afterwards. A part of the report will be compiled into a presentation of about 10 minutes.
Class Schedule	lesson1 Basic lecture on genome editing, overview of experiments, genome editing experiments using cells (transfection), in vitro cleavage experiments lesson3 Lecture on creativity by an external lecturer, listening to a presentation on an issue in a industry, group work to generate ideas for the issue lesson3 Preliminary research and preparation of presentation materials (group work) to realize the idea lesson4 Presentation of problem-solving ideas (group presentations) lesson5 Genome editing experiment using cells (observation of results), discussion of results lesson6 Discussion on ethical issues in social implementation of genome editing lesson7 Research on genome editing topics of personal interest and preparation of presentation materials lesson8 Plenary discussion (individual presentations)
Text/Reference Books,etc.	For the first, fourth, eleventh and twelfth lessons, we will use slides created by us as course materials. (The slides will be distributed via the online learning system "moodle," so please download them to your own laptop prior to the class.)
PC or AV used in Class,etc.
(More Details)
Learning techniques to be incorporated
Suggestions on Preparation and Review	Please read through the downloaded textbook in advance before taking the course or watching the class videos.
Requirements	・Due to space limitations, the maximum number of participants will be limited to six. If there are too many applicants, we will ask them to submit a 200-word explanation of why they wish to take the course, and the six applicants will be selected by drawing lots. ・The lecture will be held from the second to the fourth week of September (specific dates will be decided together with the participants at the orientation in December). ・The schedule will be decided together with the students at the orientation session (Teams) in January. ・Students are required to take out "Accident Insurance for Student Education and Research" in case of unforeseen circumstances during class hours or while returning home.
Grading Method	(1) Active participation in lectures (2) Submission of reports (3) Evaluation of presentations in plenary discussions (evaluation is also conducted within the participants) Evaluation will be on a pass/fail basis only, and will not be on a 5-step evaluation.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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