Hiroshima University Syllabus

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Japanese
Academic Year 2024Year School/Graduate School School of Pharmaceutical Sciences Program of Medicinal Sciences
Lecture Code I7035001 Subject Classification Specialized Education
Subject Name 有機反応論演習
Subject Name
(Katakana)
ユウキハンノウロンエンシュウ
Subject Name in
English
Practice of Organic Reactions
Instructor KUMAMOTO TAKUYA
Instructor
(Katakana)
クマモト タクヤ
Campus Kasumi Semester/Term 4th-Year,  First Semester,  First Semester
Days, Periods, and Classrooms (1st) Inte
Lesson Style Seminar Lesson Style
(More Details)
 
Seminar 
Credits 1.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 4 : Undergraduate Advanced
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 03 : Pharmaceutical Sciences
Eligible Students
Keywords  
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students)
 
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students)
Medicinal Sciences
(Knowledge and Understanding)
・The knowledge of chemical compounds including medicine.
(Abilities and Skills)
・Development of knowledge of chemical compounds including medicine. (application) 
Class Objectives
/Class Outline
One of the goals of this course is to mediate the principles of the relationships between structure and reactivity of organic molecules. This course will not deal with memorizing organic reactions, but will concentrate on the basic principles and methods behind the study of organic reaction mechanisms. 
Class Schedule 1. Introduction and Overview
2. Reactive Intermediates
Carbocations, carbanions, radicals, and carbenes
3. Relationship between Structure and Reactivity
Electrostatic, steric, and stereoelectronic effects
4. Linear Free Energy Relationship
The Hammett equation
5. Methods of Determining Organic Reaction Mechanisms
Identification of products, determination of the presence of an intermediate, crossover experiments, isotopic labeling, solvent effects,  kinetics, transition-state theory. and kinetic isotopic effects
6. Aliphatic Nucleophilic Substitution, Addition Reactions, Elimination Reactions, Rearrangements 
Text/Reference
Books,etc.
lecture handouts 
PC or AV used in
Class,etc.
 
(More Details) Computor projector 
Learning techniques to be incorporated  
Suggestions on
Preparation and
Review
You are required to read the lecture handouts before the class. 
Requirements  
Grading Method Grading will be determined on the basis of your performance in the discussion section. 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message  
Other   
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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