I7073001 Clinical Pharmacology A

Hiroshima University Syllabus

Japanese

Academic Year 2024Year School/Graduate School School of Pharmaceutical Sciences Program of Pharmaceutical Sciences

Lecture Code I7073001 Subject Classification Specialized Education

Subject Name 臨床薬理学Ａ

Subject Name
（Katakana）リンショウヤクリガクA

Subject Name in
English Clinical Pharmacology A

Instructor OZAWA KOICHIRO,YANASE YUHKI

Instructor
(Katakana) オザワ　コウイチロウ,ヤナセ　ユウキ

Campus Kasumi Semester/Term 4th-Year,  Second Semester,  3Term

Days, Periods, and Classrooms (3T) Weds1-4：霞R402講義室

Lesson Style Lecture Lesson Style
(More Details) 　

Lecture and using blackboard and OHP projector

Credits 2.0 Class Hours/Week 　 Language of Instruction B : Japanese／English

Course Level 3 : Undergraduate High-Intermediate

Course Area（Area） 27 : Health Sciences

Course Area（Discipline） 03 : Pharmaceutical Sciences

Eligible Students Fourth-year undergraduates of Pharmaceutical sciences

Keywords pathophysiology, pharmacotherapy, main effect and side effect, Digestive System Disease, hematologic disease,Practical work experience, cancer, infectious disease, human disease, human health, obesity, public health

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) Pharmaceutical Sciences
（Knowledge and Understanding）
・Knowledge and understanding of the biological maintenance system of homeostasis and the ability to adjust to the environment  ●credential⑤
・Fundamental knowledge・understanding about proper drug treatment for major diseases related to various organ
・Knowledge and understanding about rational analyses of pharmacokinetics in order to to understand quantitatively madicinal effects or side effects●qualities ⑥
・The knowledge and understanding of communication with medical teams relating to medication. ● quality ③、④
・The ability of considering basic pharmacological effects of medicine to chemical structure.  ●quality ⑤
・Abilities・skills of citing speculated major diseases from aberration of clinical test values●qualities⑥
（Abilities and Skills）
・Ability and skills to measure drug blood level concerning major drugs ●credential⑥
・The ability and skills of communication with medical teams relating to medication. ● quality ③、④
・The ability and skills to appropriately deal with contraindication or inappropriate treatments of medicine. ●qualities ⑥
（Attitudes）
・Self-betterment of character formation as a medical professional : the appropriate action and attitude being aware of that a pharmacist is a professional relating to human life.  The knowledge and understanding to have communication not only with ailing people but with other medical staff in a medical team.  ●quality ①　②　③　④　⑨
・Ability to be a pharmacist who is relied on not only by a medical team but also by citizens; the ability to be considerate of patients.  Qualification 1), 2), and 4).

Medicinal Sciences
（Knowledge and Understanding）
・Knowledge of human and biological bodies.
・The knowledge relating to mutual reaction between chemical compounds including medicine and a human body
（Abilities and Skills）
・Development of knowledge about human and biological bodies. (advance)
・Development of knowledge relating to mutual reaction between chemical compounds including medicine and a human body (application)

Class Objectives
/Class Outline GIO: In order to become able to contribute to appropriate medical treatment in the future, to learn the basic knowledge about pathophysiology of digestive system diseases and hematologic disease and the representative pharmaceutical products used for digestive system diseases and hematologic disease.
Summary of the class：To lecture the basic knowledge about pathophysiology of digestive system diseases and hematologic disease, the efficacy of the therapeutic drug for digestive system diseases and hematologic diseases, the side effects.

Class Schedule Digestive system diseases
lesson 1　Blood
Composition of the blood, hematopoietic mechanism and hematopoietic factor, characteristic of the blood component
lesson 2　Hematopoietic agent
Production of erythrocyte and anemia, hematopoietic agent
lesson 3: Please read “Coagulation and fibrinolytic system”of the lesson 3　Coagulation and fibrinolytic system
Coagulation factors, fibrinolytic system
lesson 4　Anticoagulant and hemostatics
Anticoagulant, antiplatelet drug, hemostatics, blood coagulation accelerant, ，antiplasmin, thrombin
lesson 5　Disseminated intravascular coagulation（DIC）
lesson 6　Haemophilia and vitamin K deficiency
lesson 7　Purpura
Idiopathic thrombocytopenic purpura (ITP), allergic purpura
Hematologic diseases
lesson 8　Esophageal disease, gastropathy, and the medicine (1)
Acute gastric mucosal lesion (AGML), chronic gastritis, stomach ulcer, gastric polyp, ，dumping syndrome
lesson 9　Esophageal disease, gastropathy, and the medicine (2)
Acute gastric mucosal lesion (AGML), chronic gastritis, stomach ulcer, gastric polyp, ，dumping syndrome
lesson 10　Intestinal disease and the medicine
Ulcerative colitis, Crohn’s disease，Irritable Bowel Syndrome, ileus
lesson 11　Constipation, diarrhea, emesis, and the medicine
lesson 12　Hepatopathy and the medicine (1)
Acute hepatitis A, acute hepatitis B, acute hepatitis C, chronic viral hepatitis
lesson 13　Hepatopathy and the medicine (2)
Liver cirrhosis, Acute hepatitis，Toxic and drug-induced hepatitis
lesson 14　Cholangia and the medicine
Cholelithiasis，cholangitis
lesson 15　Pancreatopathyand the medicine
Pancreas, acute pancreatitis, clonic pancreatitis

Text/Reference
Books,etc. Text: Resume

PC or AV used in
Class,etc. 　

(More Details) OHP and power point

Learning techniques to be incorporated 　

Suggestions on
Preparation and
Review lesson 1: Please read “Blood”of the resume and review the class.  You will take a small test in a next beginning.
lesson 2: Please read “Hematopoietic agent”of the resume and review the class.  You will take a small test in a next beginning.
lesson 3: Please read “Coagulation and fibrinolytic system”of the resume and review the class.  You will take a small test in a next beginning.
lesson 4: Please read “Anticoagulant and hemostatics”of the resume and review the class.  You will take a small test in a next beginning.
lesson 5: Please read “Disseminated intravascular coagulation（DIC）”of the resume and review the class.  You will take a small test in a next beginning.
lesson 6: Please read “Haemophilia and vitamin K deficiency”of the resume and review the class.  You will take a small test in a next beginning.
lesson 7: Please read “Purpura”of the resume and review the class.  You

Requirements

Grading Method The mid-term examination 40 points, the term examination 40 points, small tests 10 points, reports 10 points, one hundred in total.

Practical Experience Experienced

Summary of Practical Experience and Class Contents based on it A teacher who has the experience which participated in pharmacist work lectures on basic knowledge about works at a hospital and a pharmacy.

Message

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2024Year	School/Graduate School	School of Pharmaceutical Sciences Program of Pharmaceutical Sciences
Lecture Code	I7073001	Subject Classification	Specialized Education
Subject Name	臨床薬理学Ａ
Subject Name （Katakana）	リンショウヤクリガクA
Subject Name in English	Clinical Pharmacology A
Instructor	OZAWA KOICHIRO,YANASE YUHKI
Instructor (Katakana)	オザワ　コウイチロウ,ヤナセ　ユウキ
Campus	Kasumi	Semester/Term	4th-Year, Second Semester, 3Term
Days, Periods, and Classrooms	(3T) Weds1-4：霞R402講義室
Lesson Style	Lecture	Lesson Style (More Details)
Lecture and using blackboard and OHP projector
Credits	2.0	Class Hours/Week		Language of Instruction	B : Japanese／English
Course Level	3 : Undergraduate High-Intermediate
Course Area（Area）	27 : Health Sciences
Course Area（Discipline）	03 : Pharmaceutical Sciences
Eligible Students	Fourth-year undergraduates of Pharmaceutical sciences
Keywords	pathophysiology, pharmacotherapy, main effect and side effect, Digestive System Disease, hematologic disease,Practical work experience, cancer, infectious disease, human disease, human health, obesity, public health
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)	Pharmaceutical Sciences （Knowledge and Understanding）・Knowledge and understanding of the biological maintenance system of homeostasis and the ability to adjust to the environment ●credential⑤ ・Fundamental knowledge・understanding about proper drug treatment for major diseases related to various organ ・Knowledge and understanding about rational analyses of pharmacokinetics in order to to understand quantitatively madicinal effects or side effects●qualities ⑥ ・The knowledge and understanding of communication with medical teams relating to medication. ● quality ③、④ ・The ability of considering basic pharmacological effects of medicine to chemical structure. ●quality ⑤ ・Abilities・skills of citing speculated major diseases from aberration of clinical test values●qualities⑥ （Abilities and Skills）・Ability and skills to measure drug blood level concerning major drugs ●credential⑥ ・The ability and skills of communication with medical teams relating to medication. ● quality ③、④ ・The ability and skills to appropriately deal with contraindication or inappropriate treatments of medicine. ●qualities ⑥ （Attitudes）・Self-betterment of character formation as a medical professional : the appropriate action and attitude being aware of that a pharmacist is a professional relating to human life. The knowledge and understanding to have communication not only with ailing people but with other medical staff in a medical team. ●quality ①　②　③　④　⑨ ・Ability to be a pharmacist who is relied on not only by a medical team but also by citizens; the ability to be considerate of patients. Qualification 1), 2), and 4). Medicinal Sciences （Knowledge and Understanding）・Knowledge of human and biological bodies. ・The knowledge relating to mutual reaction between chemical compounds including medicine and a human body （Abilities and Skills）・Development of knowledge about human and biological bodies. (advance) ・Development of knowledge relating to mutual reaction between chemical compounds including medicine and a human body (application)
Class Objectives /Class Outline	GIO: In order to become able to contribute to appropriate medical treatment in the future, to learn the basic knowledge about pathophysiology of digestive system diseases and hematologic disease and the representative pharmaceutical products used for digestive system diseases and hematologic disease. Summary of the class：To lecture the basic knowledge about pathophysiology of digestive system diseases and hematologic disease, the efficacy of the therapeutic drug for digestive system diseases and hematologic diseases, the side effects.
Class Schedule	Digestive system diseases lesson 1　Blood Composition of the blood, hematopoietic mechanism and hematopoietic factor, characteristic of the blood component lesson 2　Hematopoietic agent Production of erythrocyte and anemia, hematopoietic agent lesson 3: Please read “Coagulation and fibrinolytic system”of the lesson 3　Coagulation and fibrinolytic system Coagulation factors, fibrinolytic system lesson 4　Anticoagulant and hemostatics Anticoagulant, antiplatelet drug, hemostatics, blood coagulation accelerant, ，antiplasmin, thrombin lesson 5　Disseminated intravascular coagulation（DIC） lesson 6　Haemophilia and vitamin K deficiency lesson 7　Purpura Idiopathic thrombocytopenic purpura (ITP), allergic purpura Hematologic diseases lesson 8　Esophageal disease, gastropathy, and the medicine (1) Acute gastric mucosal lesion (AGML), chronic gastritis, stomach ulcer, gastric polyp, ，dumping syndrome lesson 9　Esophageal disease, gastropathy, and the medicine (2) Acute gastric mucosal lesion (AGML), chronic gastritis, stomach ulcer, gastric polyp, ，dumping syndrome lesson 10　Intestinal disease and the medicine Ulcerative colitis, Crohn’s disease，Irritable Bowel Syndrome, ileus lesson 11　Constipation, diarrhea, emesis, and the medicine lesson 12　Hepatopathy and the medicine (1) Acute hepatitis A, acute hepatitis B, acute hepatitis C, chronic viral hepatitis lesson 13　Hepatopathy and the medicine (2) Liver cirrhosis, Acute hepatitis，Toxic and drug-induced hepatitis lesson 14　Cholangia and the medicine Cholelithiasis，cholangitis lesson 15　Pancreatopathyand the medicine Pancreas, acute pancreatitis, clonic pancreatitis
Text/Reference Books,etc.	Text: Resume
PC or AV used in Class,etc.
(More Details)	OHP and power point
Learning techniques to be incorporated
Suggestions on Preparation and Review	lesson 1: Please read “Blood”of the resume and review the class. You will take a small test in a next beginning. lesson 2: Please read “Hematopoietic agent”of the resume and review the class. You will take a small test in a next beginning. lesson 3: Please read “Coagulation and fibrinolytic system”of the resume and review the class. You will take a small test in a next beginning. lesson 4: Please read “Anticoagulant and hemostatics”of the resume and review the class. You will take a small test in a next beginning. lesson 5: Please read “Disseminated intravascular coagulation（DIC）”of the resume and review the class. You will take a small test in a next beginning. lesson 6: Please read “Haemophilia and vitamin K deficiency”of the resume and review the class. You will take a small test in a next beginning. lesson 7: Please read “Purpura”of the resume and review the class. You
Requirements
Grading Method	The mid-term examination 40 points, the term examination 40 points, small tests 10 points, reports 10 points, one hundred in total.
Practical Experience	Experienced
Summary of Practical Experience and Class Contents based on it	A teacher who has the experience which participated in pharmacist work lectures on basic knowledge about works at a hospital and a pharmacy.
Message
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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