Hiroshima University Syllabus

Back to syllabus main page
Academic Year 2024Year School/Graduate School School of Pharmaceutical Sciences Program of Pharmaceutical Sciences
Lecture Code I7025001 Subject Classification Specialized Education
Subject Name 天然物薬品構造化学
Subject Name
Subject Name in
Natural Products Chemistry
マツナミ カツヨシ
Campus Kasumi Semester/Term 2nd-Year,  First Semester,  1Term
Days, Periods, and Classrooms (1T) Weds1-4:霞R404講義室
Lesson Style Lecture Lesson Style
(More Details)
Lecture (power point slide, writing on the blackboard, quiz) 
Credits 2.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 03 : Pharmaceutical Sciences
Eligible Students 2nd year student
Keywords SDG_03, SDG_04, Natural products chemistry, biosynthesis, polyketide, phenylpropanoid, lignan, flavonoid, terpene
Spectral analysis, chemical structure, IR, UV, MS, NMR 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
Pharmaceutical Sciences
(Knowledge and Understanding)
・The basic knowledge and understanding of basic structures, physical characters and reaction of medicine and other inorganic and organic compounds. ●quality ⑤

Medicinal Sciences
(Knowledge and Understanding)
・The knowledge of chemical compounds including medicine. 
Class Objectives
/Class Outline
To learn
(1) how to solve the chemical structures by spectroscopic method.
(2) plant origins, biosynthetic pathway, and pharmacological activity of various natural products. 
Class Schedule lesson1 Infrared (IR) and Ultraviolet-Visible (UV-VIS) spectroscopy
lesson2 Mass spectroscopy (MS)
lesson3 1H NMR (proton Nuclear Magnetic Resonance) spectroscopy
lesson4 13C NMR (carbon Nuclear Magnetic Resonance) spectroscopy
lesson5 2D(two dimentional)-NMR spectroscopy
lesson6 Structural analysis
lesson7 Midterm exam (Structural analysis by spectroscopy)
lesson8 Fundamental biosynthetic pathways
lesson9 Acetate malonate pathway for polyketide biosynthesis
lesson10 Shikimic acid pathway for phenylpropanoid biosyhthesis
lesson11 Biosynthesis of lignan related compounds
lesson12 Biosynthesis of flavonoids and tannins
lesson13 Mevalonate and non-mevalonate pathways
lesson14 Mono-, sesqui-, di-, sester-, tri- and tetraterpenes
lesson15 Final exam (Natural products chemistry)

Mid-term, final exam, and quiz 
Partner Natural products chemistry (Nankodo) 
PC or AV used in
(More Details) Text, slide presentation, and writing on the blackboard 
Learning techniques to be incorporated  
Suggestions on
Preparation and
Review the lecture with the textbook 
Grading Method Midterm exam (40) , final exam (40), quiz (20)
Criterion for passing: ≧60 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message Questions are welcomed at any time via email or in person. However, in the case of in-person meetings, prior contact via email is preferred. 
Other References: Medicinal Natural Products (Paul M Dewick, John Wiley & Sons, Ltd.)
Spectrometric Identification of Organic Compounds (Robert M. Silverstein et al., John Wiley & Sons, Ltd.)
Organic Chemistry: Structure and Function (K. Peter C. Vollhardt,‎ Neil E. Shore, WH Freeman)
In this course, students will master the content of the following SBOs.
C2-(4)-①-1, C2-(4)-①-2, C2-(4)-①-3, C2-(4)-①-4, C2-(4)-①-5, C2-(4)-①-6, C2-(4)-②-1, C2-(4)-③-1, C2-(5)-①-1, C2-(5)-①-2, C2-(5)-①-3, C2-(5)-①-4, C3-(4)-①-1, C3-(4)-①-2, C3-(4)-①-3, C3-(4)-①-4, C3-(4)-①-5, C3-(4)-②-1, C3-(4)-②-2, C3-(4)-③-1, C3-(4)-③-2, C3-(4)-③-3, C3-(4)-③-4, C3-(4)-④-1, C5-(1)-①-1, C5-(1)-①-2, C5-(1)-①-3, C5-(1)-①-4, C5-(1)-②-1, C5-(1)-③-1, C5-(1)-③-2, C5-(2)-①-1, C5-(2)-①-2, C5-(2)-①-3, C5-(2)-①-4, C5-(2)-①-5, C5-(2)-②-1, C5-(2)-②-2, C5-(2)-③-1, C5-(2)-④-1, C5-(2)-④-2, C5-(2)-④-3 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
Back to syllabus main page