Hiroshima University Syllabus

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Academic Year 2024Year School/Graduate School School of Applied Biological Science
Lecture Code L5003004 Subject Classification Specialized Education
Subject Name ゲノム科学II
Subject Name
Subject Name in
Genome Science II
フジカワ ユキチ,サンボンギ ヨシヒロ,フジイ ソウタロウ
Campus Higashi-Hiroshima Semester/Term 2nd-Year,  Second Semester,  3Term
Days, Periods, and Classrooms (3T) Fri1-4:ABS C301
Lesson Style Lecture Lesson Style
(More Details)
Credits 2.0 Class Hours/Week   Language of Instruction J : Japanese
Course Level 3 : Undergraduate High-Intermediate
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 01 : Agricultural Sciences
Eligible Students The required subject of the Molecular Agro-Life Science Program
Keywords Check keywords in the Class schedule below. 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
Food Science Program
(Knowledge and Understanding)
・Ability for comprehensive and crossdisciplinary thinking and knowledge / understandings required to see a phenomena from a broad, top-down perspective and to take action for solving problems regarding the specialized area.
・Basic knowledge of such as chemistry, biology, biochemistry, microbiology, physics, and mathematics required for understanding food science.

Molecular Agro-Life Science Program
(Knowledge and Understanding)
・Knowledge and understanding regarding organic molecule, cell, individual organism, and population 
Class Objectives
/Class Outline
Students will learn about the basics of protein and enzyme chemistry, especially about properties and characteristics of enzyme/protein.
Lecture will be provided by two or three faculty members of the Molecular Agro-Life Science Program. 
Class Schedule Lesson1: Amino acids and four levels of organization in the structure of the protein (Sambongi)
  Polypeptide, side chain, noncovalent bond, primary structure, secondary structure, tertiary structure, quaternary structure
Lesson2: Protein conformation and bond angle in polypeptide(Sambongi,Fujii),
  Ramachandran plot, α helix, β sheet, domain
Lesson3: Various proteins found in organisms(Sambongi),
  Hemoglobin, actin,  collagen, capsid of virus, amyloid, prion disease
Lesson4: How cells obtain energy from food(Sambongi),
  ATP, glycolysis, citric acid cycle, substrate-level phosphorylation
Lesson5: Mitochondria and its energy conversion(Sambongi),
  Chemiosmotic coupling, respiratory chain, ATP synthase, oxidative phosphorylation
Lesson6: Chloroplasts and photosynthesis Light reaction and Dark reaction(Sambongi),
  Chlorophyll, Charge separation, Photosystem, Cytochrome bf, Z scheme, Ferredoxin-NADP+ reductase, Calvin cycle, Rubisco, Photorespiration, C4 photosynthesis
Lesson7:Examination (Lesson 1 to 6) (Sambongi, Fujii)

Lesson8: Catalytic reaction of cell(Fujikawa)
  Chemical reaction, enzyme reaction, enzyme specificity
Lesson9: Enzyme catalytic mechanism 1(Fujikawa)
Transition state theory, catalytic group, binding site
Lesson10:Enzyme catalytic mechanism 2(Fujikawa)
General acid / base catalyst, covalent bond catalyst, reaction induction
Lesson11: Kinetics of enzyme(Fujikawa)
Substrate concentration, enzyme reaction rate, Michaelis constant
Lesson12:  Regulation mechanism of enzyme activity(Fujikawa)
Lesson13: Regulation mechanism of enzyme activity I(Fujikawa)
temperature, pH ,Regulator, covalent chemical modification, limited hydrolysis
Lesson14:  Regulation mechanism of enzyme activity II(Fujikawa)
Lesson15: Examination (Lesson 8 to 14) (Fujikawa)

Lesson 1 to 6: Examination
Lesson 8 to 14: Examination  
Molecular Biology of the Cell 4th, 5th, and 6th editions 
PC or AV used in
(More Details) Handouts, Projector 
Learning techniques to be incorporated  
Suggestions on
Preparation and
Before taking each lesson, study the meaning of keywords.
After each lesson, review the lesson. 
Grading Method Examination
(A student, absent over 5 times, is not subject to an academic assessment) 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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