Hiroshima University Syllabus

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Academic Year 2024Year School/Graduate School School of Dentistry Program of Dentistry
Lecture Code J1505050 Subject Classification Specialized Education
Subject Name 薬理学実習
Subject Name
Subject Name in
Practice of Pharmacology
アゴウ ユキオ,アオト カズシ,ヨコヤマ レイ,アサノ サトシ
Campus Kasumi Semester/Term 3rd-Year,  First Semester,  1Term
Days, Periods, and Classrooms (1T) Fri5-8:DEN Training Rm 1
Lesson Style Practical Lesson Style
(More Details)
Experiments, Use of mice and guinea pigs, Use of chemicals, Drug administration
In some cases, we will use on-demand materials. 
Credits 1.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 3 : Undergraduate High-Intermediate
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 04 : Life Sciences
Eligible Students 3rd
Keywords Pharmacology, Dental Pharmacology 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
Pharmacology is 'the study of the relationship between drugs and living organisms' and is closely related to biology, biochemistry, anatomy, physiology, pathobiochemistry, pathophysiology and pharmacotherapeutics. In pharmacology practice, in vivo experiments are mainly carried out on laboratory animals to learn the proper handling of typical laboratory animals and typical administration methods, and to deepen understanding of analgesics and drugs that affect the sensory and central nervous systems. Students acquire basic skills in pharmacological experiments by observing the effects of various drugs and further develop their understanding of pharmacology and other biological subjects.  
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
(Knowledge and Understanding)
・Knowledge regarding basic and clinical dental medicine
・Knowledge of life sciences
(Abilities and Skills)
・Basic skills required for conducting experiments and presentations
(Comprehensive Abilities)
・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice 
Class Objectives
/Class Outline
In the practice of pharmacology, you will conduct experiments using lab animals and excised organs on the effects of bioactive substances and drugs used in general treatment, and then you can learn how to evaluate the experimental results. This will also deepen your understanding of the adverse effects of drugs and drug-drug interaction. 
Class Schedule Lesson 1: Guidance and injection of the drug to the mouse
Lesson 2: Pain assessment and opioid for analgesia in mice
Lesson 3: Behavioral analysis of brain monoaminergic drugs
Lesson 4: Neurochemical analysis of brain monoamine neurotransmitters
Lesson 5: Hypnotic drug and pharmacokinetic drug-drug interaction
Lesson 6: Pain relief effects of local anesthetics
Lesson 7: Convulsions and local anesthetic systemic toxicity
Lesson 8: Pharmacological action of drugs acting on the parasympathetic nervous system

Submit reports after the practice. 
Training books and/or supplemental materials helpful for detailed understanding of experimental design are handed out before each practice. 
PC or AV used in
(More Details) We will also incorporate practical training using on-demand materials such as Moodle, Stream, or Teams. 
Learning techniques to be incorporated  
Suggestions on
Preparation and
・Before starting animal experiments, carefully read the training books or prints distributed in advance.
・Review the lecture materials of pharmacology in the previous year for basic knowledge about the drugs to be used. 
Requirements ・Unless there is a special reason (hospitalization, bereavement, etc.), late arrival, leaving early, and absence are not permitted. If needed, please submit appropriate procedures (reasons, etc.) to the Student Support Office in advance and contact the instructor in charge.
・If you are late, leave early, or are absent without permission, credits will not be accepted.
・Please bring a mask, lab coat, and name tag and wear them. Gloves will be prepared by the instructor.
・If you have any animal allergies, please inform the instructor in advance.
・If you feel sick or injured during the practice, notify the instructor immediately.
・Because you handle living animals, needles, and drugs, please follow the instructions of the instructor and carry out the experiment with due consideration for safety. 
Grading Method Comprehensive evaluation will be made based on the attitude of participating in the practice and the experimental report after completing the practice.
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message Animal Welfare is the desire to implement humane care and use standards for animals in research, testing, teaching, and exhibition. Animal welfare is based on the belief that animals can contribute to human welfare by providing food, fiber, work, companionship, entertainment, or by serving biomedical research or education, and humans have moral obligations to provide for the well-being of animals. 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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