J1504100 Immunology

Hiroshima University Syllabus

Japanese

Academic Year 2025Year School/Graduate School School of Dentistry Program of Dentistry

Lecture Code J1504100 Subject Classification Specialized Education

Subject Name 免疫学

Subject Name
（Katakana）メンエキガク

Subject Name in
English Immunology

Instructor TOBIUME KEI

Instructor
(Katakana) トビウメ　ケイ

Campus Kasumi Semester/Term 2nd-Year, Second Semester, 4Term

Days, Periods, and Classrooms (4T) Thur1-4：DEN Large Lecture Rm

Lesson Style Lecture Lesson Style
(More Details) Face-to-face

Immunology lecture at 2024-2025 winter season will be done on-demand video streaming as well as face-to-face class.

Credits 2.0 Class Hours/Week 4 Language of Instruction B : Japanese／English

Course Level 2 : Undergraduate Low-Intermediate

Course Area（Area） 27 : Health Sciences

Course Area（Discipline） 02 : Dental Sciences

Eligible Students Japanese as well as international foreign students, undergraduate 2nd grade.

Keywords Immune system, immune responses, innate immunity, adaptive immunity, autoimmunity, infectious immunity

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
(Applicable only to targeted subjects for undergraduate students) This immunological program should be categorized to the important discipline belonging to life science, basic dental science, experimental medicine, etc.
Criterion referenced
Evaluation
(Applicable only to targeted subjects for undergraduate students) Dentistry
（Knowledge and Understanding）
・Knowledge regarding basic and clinical dental medicine
・Knowledge of life sciences
（Comprehensive Abilities）
・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice

Class Objectives
/Class Outline Immunity is defined as resistance to disease, specifically infectious or inflammatory disease. The collection of molecules, cells, and tissues that mediate resistance to infections is called the immune system, and the coordinated reaction of these molecules and cells is the immune response. Immunology is the study of the immune system and its responses to invading pathogens which enter our body via the mucosal and skin surfaces. The physiologic function of the immune system is usually to prevent infections and to eradicate established infections.

The following questions are addressed in this class:
• What types of immune responses protect individuals from infections?
• What are the important characteristics of mucosal as well as systemic immunity, and what mechanisms are responsible for these characteristics?
• How are the cells and tissues of the immune system organized to find microbes and respond to them in ways that lead to their elimination?

Class Schedule 1, Basic concept of immunity
2, The immune system
3, Complement, NK cell, Cytokine
4, Antigen presentation
5, Thymus and T cell development
6, Leukocyte trafficking
7, Induction of T cell mediated adaptive immunity
8, Effector phase of T cell mediated adaptive immunity
9, B cell mediated adaptive immunity
10, The mucosal immune system
11, Immunological tolerance and autoimmunity
12, Allergy
13, Vaccine
14, Examination of immunology

Paper examination

Text/Reference
Books,etc. Janeway's immunobiology 10th edition, W. W. Norton & Company

PC or AV used in
Class,etc. Text, Handouts, moodle

(More Details) on-demand video streaming and handout at hirodai moodle

Learning techniques to be incorporated Discussions, PBL (Problem-based Learning)/ TBL (Team-based Learning), Post-class Report

Suggestions on
Preparation and
Review This class will be proceeded based on Janeway's immunobiology 10th edition.

Requirements When the lecture will be scheduled as face to face style, you have to attend and actively participate the class at the large lecture room, A-building, 6th floor. If you are not able to come, you have to submit either documents or certificates that the third parties assure you have serious/clear reasons for your absence in the lecture.

Grading Method The credit of immunology will be evaluated based on the paper examination.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2025Year	School/Graduate School	School of Dentistry Program of Dentistry
Lecture Code	J1504100	Subject Classification	Specialized Education
Subject Name	免疫学
Subject Name （Katakana）	メンエキガク
Subject Name in English	Immunology
Instructor	TOBIUME KEI
Instructor (Katakana)	トビウメ　ケイ
Campus	Kasumi	Semester/Term	2nd-Year, Second Semester, 4Term
Days, Periods, and Classrooms	(4T) Thur1-4：DEN Large Lecture Rm
Lesson Style	Lecture	Lesson Style (More Details)	Face-to-face
Immunology lecture at 2024-2025 winter season will be done on-demand video streaming as well as face-to-face class.
Credits	2.0	Class Hours/Week	4	Language of Instruction	B : Japanese／English
Course Level	2 : Undergraduate Low-Intermediate
Course Area（Area）	27 : Health Sciences
Course Area（Discipline）	02 : Dental Sciences
Eligible Students	Japanese as well as international foreign students, undergraduate 2nd grade.
Keywords	Immune system, immune responses, innate immunity, adaptive immunity, autoimmunity, infectious immunity
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program (Applicable only to targeted subjects for undergraduate students)	This immunological program should be categorized to the important discipline belonging to life science, basic dental science, experimental medicine, etc.
Criterion referenced Evaluation (Applicable only to targeted subjects for undergraduate students)	Dentistry （Knowledge and Understanding）・Knowledge regarding basic and clinical dental medicine ・Knowledge of life sciences （Comprehensive Abilities）・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice
Class Objectives /Class Outline	Immunity is defined as resistance to disease, specifically infectious or inflammatory disease. The collection of molecules, cells, and tissues that mediate resistance to infections is called the immune system, and the coordinated reaction of these molecules and cells is the immune response. Immunology is the study of the immune system and its responses to invading pathogens which enter our body via the mucosal and skin surfaces. The physiologic function of the immune system is usually to prevent infections and to eradicate established infections. The following questions are addressed in this class: • What types of immune responses protect individuals from infections? • What are the important characteristics of mucosal as well as systemic immunity, and what mechanisms are responsible for these characteristics? • How are the cells and tissues of the immune system organized to find microbes and respond to them in ways that lead to their elimination?
Class Schedule	1, Basic concept of immunity 2, The immune system 3, Complement, NK cell, Cytokine 4, Antigen presentation 5, Thymus and T cell development 6, Leukocyte trafficking 7, Induction of T cell mediated adaptive immunity 8, Effector phase of T cell mediated adaptive immunity 9, B cell mediated adaptive immunity 10, The mucosal immune system 11, Immunological tolerance and autoimmunity 12, Allergy 13, Vaccine 14, Examination of immunology Paper examination
Text/Reference Books,etc.	Janeway's immunobiology 10th edition, W. W. Norton & Company
PC or AV used in Class,etc.	Text, Handouts, moodle
(More Details)	on-demand video streaming and handout at hirodai moodle
Learning techniques to be incorporated	Discussions, PBL (Problem-based Learning)/ TBL (Team-based Learning), Post-class Report
Suggestions on Preparation and Review	This class will be proceeded based on Janeway's immunobiology 10th edition.
Requirements	When the lecture will be scheduled as face to face style, you have to attend and actively participate the class at the large lecture room, A-building, 6th floor. If you are not able to come, you have to submit either documents or certificates that the third parties assure you have serious/clear reasons for your absence in the lecture.
Grading Method	The credit of immunology will be evaluated based on the paper examination.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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