Hiroshima University Syllabus

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Academic Year 2024Year School/Graduate School School of Pharmaceutical Sciences Program of Pharmaceutical Sciences
Lecture Code I7154012 Subject Classification Specialized Education
Subject Name 臨床研究I
Subject Name
Subject Name in
Special laboratory Works in Clinical Pharmacy I
モリオカ ノリミツ,ナカシマ カズエ
Campus Kasumi Semester/Term 5th-Year,  First Semester,  Year
Days, Periods, and Classrooms (Year) Inte
Lesson Style Seminar Lesson Style
(More Details)
laboratory work; analysis and discussion; using chemicals, animals, and cultured cells 
Credits 2.0 Class Hours/Week   Language of Instruction J : Japanese
Course Level 4 : Undergraduate Advanced
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 03 : Pharmaceutical Sciences
Eligible Students Undergraduates of Pharmaceutical sciences
Keywords SDG_03 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
Pharmaceutical Sciences
(Abilities and Skills)
・Abilities of collecting necessary information of drug treatment her/him self  ●qualities⑥
・Ability and skills to measure drug blood level concerning major drugs ●credential⑥
(Comprehensive Abilities)
・Comprehensive problem-solving ability and educational ability: Concerning the influences caused by numerous chemical substances existing on the earth, to be able to analyze and argue about the survival  of the human race. Also, to have the ability and skills to give instruction to youth.●credential ⑤,⑩
・The research ability: the ability to select issues to be solved in the professional field of pharmacist and carry out measures and research to solve the issues.  ●quality ⑧ 
Class Objectives
/Class Outline
GIO:In order to contribute to progress and improvement of pharmaceutical care, to master  the ability for problem discovery and problem-solving.
Summary of the class: Our goal is clarifying the pathogenic mechanism at the molecular level and trying to search for the therapeutic drug.  In order to reach the goal, you will draw up a study and plan it and try experiments and analyze the data, after that you will make a original paper written in English. 
Class Schedule 1) Introduction
2) Methods of feeding experimental animals
3) How to handle experimental animals
4) Preparation of experimental animal models (neuropathic pain PSNL model)
5) Preparation of experimental animal models (neuropathic pain SNI model)
6) Preparation of experimental animal models (trigeminal neuropathy model)
7) Preparation of experimental animal models (osteoarthritis model)
8) Behavioral evaluation of animal models (nociceptive behaviors)
9) Behavioral evaluation of animal models (depressive and anxiety-like behaviors)
10) Behavioral evaluation of animal models (cognitive functional behaviors)
11) Preparation of RNA from animal models
12) Preparation of protein from animal models
13) Immunohistochemistry (tissue fixation)
14) Immunohistochemistry (preparation of tissue slice)
15) Immunohistochemistry (reaction and evaluation) 
You will makes resumes and presentation files with power point. 
PC or AV used in
(More Details)  
Learning techniques to be incorporated  
Suggestions on
Preparation and
Please read particular part of the resume and review the class and keep to read particular paper about each topic and to take a look at associated articles. You will make resumes and presentation files with power point and the English article by yourself. 
Requirements In order to take this class, your should meet the promotion standards for higher grade. 
Grading Method Attitude 10 points, making own study purpose and experimental planes 10 points, experimental skills 20 points, ability for analyzing and discussion 20 points, making presentation files 20points, making a graduation thesis 20 points; 100 points in total. 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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