Hiroshima University Syllabus

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Academic Year 2024Year School/Graduate School School of Pharmaceutical Sciences Program of Pharmaceutical Sciences
Lecture Code I7052001 Subject Classification Specialized Education
Subject Name 薬物動態解析学
Subject Name
Subject Name in
ウチダ ヤスオ,カワミ マサシ
Campus Kasumi Semester/Term 3rd-Year,  First Semester,  1Term
Days, Periods, and Classrooms (1T) Weds1-4:PHS Lecture Rm 2
Lesson Style Lecture Lesson Style
(More Details)
Lecture and a chalk talk 
Credits 2.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 3 : Undergraduate High-Intermediate
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 03 : Pharmaceutical Sciences
Eligible Students
Keywords Pharmacokinetics, compartment model, nonlinear PK, moment analysis 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
Pharmaceutical Sciences
(Knowledge and Understanding)
・Knowledge and understanding about rational analyses of pharmacokinetics in order to to understand quantitatively madicinal effects or side effects. ●quality ⑥
(Abilities and Skills)
・Abilities・skills of thinking ways of coping to reduce harmful effects(side effects) of madicine. ●quality ⑤

Medicinal Sciences
(Knowledge and Understanding)
・The knowledge relating to mutual reaction between chemical compounds including medicine and a human body 
Class Objectives
/Class Outline
The course objective is to obtain knowledge about Pharmacokinetics and to theoretically understand Pharmacokinetics 
Class Schedule lesson1: IImportance of pharmacokinetics (PK)
lesson2: Compartment model
lesson3:  PK in the i.v. administration; Analysis based on drug concentration in plasma
lesson4:  PK in the i.v. administration; Analysis based on drug concentration in urine
lesson5:  PK for the i.v. drip administration
lesson6:  PK for the p.o. administration
lesson7:  PK for the repeated administration
lesson8:  2-compartment model
lesson9:  Moment analysis
lesson10:  Clearance theory①
lesson11:  Clearance theory②
lesson12:  Clearance theory③
lesson13:  Nonlinear Pharmacokinetics
lesson14:  TDM①
lesson15:  TDM② 
Biopharmaceutics published by Nankodo (Editors; Hayashi & Tanigawara) 
PC or AV used in
(More Details) PowerPoint presentation, a chalk talk, prints, textbook 
Learning techniques to be incorporated  
Suggestions on
Preparation and
Please contact early if you have some questions. 
Requirements A calculator is required for exercises. 
Grading Method Grading will be based on the results of examination (a midterm examination 50 marks, a term end examination 50 marks). More than 60 marks in total is necessary to get a credit of this class. 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message Lectures are mainly conducted in Japanese and partly in English. Lecture materials are written in both Japanese and English. 
Other Related SBOs
【E4-(2)-①-1~6, E4-(2)-②-1~4, E5-(2)-③-1】 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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