Hiroshima University Syllabus

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Academic Year 2024Year School/Graduate School School of Dentistry Program of Dentistry
Lecture Code J1504100 Subject Classification Specialized Education
Subject Name 免疫学
Subject Name
Subject Name in
タカハシ イチロウ,シマオカ モトム,クニサワ ジュン,トビウメ ケイ
Campus Kasumi Semester/Term 2nd-Year,  Second Semester,  4Term
Days, Periods, and Classrooms (4T) Thur1-4:DEN Large Lecture Rm
Lesson Style Lecture Lesson Style
(More Details)
Immunology lecture at 2024-2025 winter season will be done on-demand video streaming as well as face-to-face class. 
Credits 2.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 02 : Dental Sciences
Eligible Students Japanese as well as international foreign students, undergraduate 2nd grade.
Keywords Immune system, immune responses, innate immunity, adaptive immunity, autoimmunity, infectious immunity 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
(Applicable only to targeted subjects for undergraduate students)
This immunological program should be categorized to the important discipline belonging to life science, basic dental science, experimental medicine, etc. 
Criterion referenced
(Applicable only to targeted subjects for undergraduate students)
(Knowledge and Understanding)
・Knowledge regarding basic and clinical dental medicine
・Knowledge of life sciences
(Comprehensive Abilities)
・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice 
Class Objectives
/Class Outline
Immunity is defined as resistance to disease, specifically infectious or inflammatory disease. The collection of molecules, cells, and tissues that mediate resistance to infections is called the immune system, and the coordinated reaction of these molecules and cells is the immune response. Immunology is the study of the immune system and its responses to invading pathogens which enter our body via the mucosal and skin surfaces. The physiologic function of the immune system is usually to prevent infections and to eradicate established infections.

The following questions are addressed in this class:
• What types of immune responses protect individuals from infections?
• What are the important characteristics of mucosal as well as systemic immunity, and what mechanisms are responsible for these characteristics?
• How are the cells and tissues of the immune system organized to find microbes and respond to them in ways that lead to their elimination?
Class Schedule 1, Basic concept of immunity: Takahashi (face to face)
2, The immune system: Takahashi (face to face)
3, Complement, NK cell, Cytokine: Takahashi (face to face)
4, Antigen presentation: Takahashi (face to face)
5, Thymus and T cell development: Takahashi (on-demand movie)
6, Leukocyte trafficking: Shimaoka (on-demand movie)
7, Induction of T cell mediated adaptive immunity: Takahashi (face to face)
8, Effector phase of T cell mediated adaptive immunity: Takahashi (face to face)
9, B cell mediated adaptive immunity: Takahashi (face to face)
10, The mucosal immune system: Takahashi (face to face)
11, Immunological tolerance and autoimmunity: Tobiume (face to face)
12, Allergy: Tobiume (face to face)
13, Vaccine: Kunisawa (on-demand movie)
14, Examination of immunology: Takahashi

Paper examination will be scheduled on January 30th, 2025. 
Janeway's immunobiology 10th edition, W. W. Norton & Company 
PC or AV used in
(More Details) on-demand video streaming and handout at hirodai moodle 
Learning techniques to be incorporated  
Suggestions on
Preparation and
This class will be proceeded based on Janeway's immunobiology 10th edition. 
Requirements When the lecture will be scheduled as face to face style, you have to attend and actively participate the class at the large lecture room, A-building, 6th floor. If you are not able to come, you have to submit either documents or certificates that the third parties assure you have serious/clear reasons for your absence in the lecture. 
Grading Method The credit of immunology will be evaluated based on the paper examination on January 30th, 2025. 
Practical Experience Experienced  
Summary of Practical Experience and Class Contents based on it Lecturers in this class have experienced immunological research programs at Osaka University, Research Institute for Microbial Diseases, Tokyo University, Institute of Medical Sciences, Harvard Medical School, La Jolla Institute for Allergy and Immunology, et al. 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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