| Academic Year |
2022Year |
School/Graduate School |
School of Pharmaceutical Sciences Program of Pharmaceutical Sciences |
| Lecture Code |
I7052001 |
Subject Classification |
Specialized Education |
| Subject Name |
薬物動態解析学 |
Subject Name
（Katakana） |
ヤクブツドウタイカイセキガク |
Subject Name in
English |
Pharmacokinetics |
| Instructor |
YUMOTO RYOKO,TAKANO MIKIHISA |
Instructor
(Katakana) |
ユモト リョウコ,タカノ ミキヒサ |
| Campus |
Kasumi |
Semester/Term |
3rd-Year, First Semester, 1Term |
| Days, Periods, and Classrooms |
(1T) Weds1-4：PHS Lecture Rm 2 |
| Lesson Style |
Lecture |
Lesson Style
(More Details) |
|
| Lecture and a chalk talk |
| Credits |
2.0 |
Class Hours/Week |
|
Language of Instruction |
B
:
Japanese／English |
| Course Level |
3
:
Undergraduate High-Intermediate
|
| Course Area（Area） |
27
:
Health Sciences |
| Course Area（Discipline） |
03
:
Pharmaceutical Sciences |
| Eligible Students |
|
| Keywords |
Pharmacokinetics, compartment model, nonlinear PK, moment analysis |
| Special Subject for Teacher Education |
|
Special Subject |
|
Class Status
within Educational
Program | |
|---|
Criterion referenced
Evaluation | Pharmaceutical Sciences
（Knowledge and Understanding）
・Knowledge and understanding about rational analyses of pharmacokinetics in order to to understand quantitatively madicinal effects or side effects●qualities ⑥
（Abilities and Skills）
・Abilities・skills of thinking ways of coping to reduce harmful effects(side effects) of madicine●qualities⑤
Medicinal Sciences
（Knowledge and Understanding）
・The knowledge relating to mutual reaction between chemical compounds including medicine and a human body |
|---|
Class Objectives
/Class Outline |
The course objective is to obtain knowledge about Pharmacokinetics and to theoretically understand Pharmacokinetics |
| Class Schedule |
lesson1: Importance of pharmacokinetics (PK)
lesson2: Three basic PK parameters
lesson3: Compartment model
lesson4: PK after i.v. injection (Based on the drug concentrations in plasma)
lesson5: PK after i.v. injection (Based on the drug concentration in urine)
lesson6: PK after i.v. infusion
lesson7: PK after p.o. administration
lesson8: PK after repeated administration
lesson9: Therapeutic Drug Monitoring (TDM)
lesson10: Non-linear PK
lesson11: Dosage adjustment in disease states
lesson12: Physiological PK
lesson13: Tissue clearance and intrinsic clearance
lesson14: First-pass effect
lesson15: Moment analysis |
Text/Reference
Books,etc. |
Biopharmaceutics published by Nankodo (Editors; Hayashi & Tanigawara) |
PC or AV used in
Class,etc. |
|
| (More Details) |
PowerPoint presentation, a chalk talk, prints, textbook |
| Learning techniques to be incorporated |
|
Suggestions on
Preparation and
Review |
Please contact early if you have some questions. |
| Requirements |
A calculator is required for exercises. |
| Grading Method |
Grading will be based on the results of examination (a midterm examination 50 marks, a term end examination 50 marks). More than 60 marks in total is necessary to get a credit of this class. |
| Practical Experience |
|
| Summary of Practical Experience and Class Contents based on it |
|
| Message |
Lectures are mainly conducted in Japanese and partly in English. Lecture materials are written in both Japanese and English. |
| Other |
Related SBOs
【E4-(2)-①-1～6, E4-(2)-②-3, E5-(2)-③-1】 |
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. |