Hiroshima University Syllabus

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Academic Year 2022Year School/Graduate School School of Engineering
Lecture Code K7359030 Subject Classification Specialized Education
Subject Name 酵素化学
Subject Name
Subject Name in
Enzyme Chemistry
アキ ツネヒロ
Campus Higashi-Hiroshima Semester/Term 2nd-Year,  Second Semester,  3Term
Days, Periods, and Classrooms (3T) Tues1-2,Fri1-2:ENG 117
Lesson Style Lecture Lesson Style
(More Details)
Credits 2.0 Class Hours/Week   Language of Instruction B : Japanese/English
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 02 : Biotechnology
Eligible Students Faculty of Engineering, Cluster III, second grade
Keywords Properties of enzyme, Measurement, kinetics and machinery of enzyme reaction 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Criterion referenced
Program of Biotechnology
(Knowledge and Understanding)
・Acquisition of basic and advanced knowledge relating to biotechnology and life science. (Target/Lecture class) 
Class Objectives
/Class Outline
General property and molecular structure of enzymes, kinetics and machinery of enzymes reactions, and methods for purification, measurement and utilization in industrial field are mentioned. Students will be able to learn about the rudiments as well as forefront on the enzyme research. 
Class Schedule 1. Introduction: grouping and naming of enzymes, history of enzyme research
2. Molecular structure and function of enzyme
3, 4. Chemistry of active center in enzyme: substrate specificity, coenzyme
5, 6. Kinetics: effect of temperature, pH and substrate concentration
7, 8. Kinetics: inhibition reaction, two-substrates reaction
9. Summary of property and kinetics of enzyme.
  Basic of electron transfer in chemical reaction
10-12. Machinery of enzyme reaction: catalytic mechanism
13, 14. Machinery of enzyme reaction: lysozyme, serine protease
15. Utilization of enzyme: food, medicine, and environment

Examination: end of term
Homework: submission of report 
Text: Biochemistry, 4th Edition, Donald Voet & Judith G. Voet (Tokyo Kagaku Dojin)
Subtext: Enzyme: Science and Engineering, Tetsuo Toratani, et al. (Kodansha) 
PC or AV used in
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Learning techniques to be incorporated  
Suggestions on
Preparation and
Preparations: Read corresponding part of the text.
Review: Use problems in the text and related materials. 
Grading Method Term examination (80%) and reports (20%) 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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