Hiroshima University Syllabus

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Japanese
Academic Year 2022Year School/Graduate School School of Engineering
Lecture Code K7352030 Subject Classification Specialized Education
Subject Name 生物有機化学
Subject Name
(Katakana)
セイブツユウキカガク
Subject Name in
English
Bioorganic Chemistry
Instructor ARAKAWA KENJI
Instructor
(Katakana)
アラカワ ケンジ
Campus Higashi-Hiroshima Semester/Term 3rd-Year,  First Semester,  1Term
Days, Periods, and Classrooms (1T) Tues3-4,Thur3-4:ENG 114
Lesson Style Lecture Lesson Style
(More Details)
 
Lecture
[Notice] This lecture may be provided by online lectures (on-demand)  when COVID-19 crisis still has a problem. I will announce the type of lecture when necessary. 
Credits 2.0 Class Hours/Week   Language of Instruction J : Japanese
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 03 : Basic Biology
Eligible Students
Keywords  
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Program
 
Criterion referenced
Evaluation
Program of Applied Chemistry
(Knowledge and Understanding)
・Wide range of basic knowledge on liberal arts and specialized education, and professional basic knowledge on chemistry.
・Advanced technical knowledge of applied chemistry.
・The conception ability based on logical thinking supported by basic and technical knowledge.

Program of Biotechnology
(Knowledge and Understanding)
・Acquisition of basic and advanced knowledge relating to biotechnology and life science. (Target/Lecture class) 
Class Objectives
/Class Outline
This lecture introduces about chemical reaction and chemical compounds  involved in biological activities in wide variety of living organisms.  
Class Schedule lesson1 Functional group important for biological chemistry
McMurry 1.1 Functional Groups in Biological Chemistry
McMurry 1.2 Acids and Bases; Electrophiles and Nucleophiles
lesson2 Mechanisms: Electrophilic Addition Reactions, Nucleophilic Substitution Reactions
McMurry 1.3 Mechanisms: Electrophilic Addition Reactions
McMurry 1.4 Mechanisms: Aromatic nucleophilic Substitution Reactions
McMurry 1.5 Mechanisms: Aliphatic nucleophilic Substitution Reactions
lesson3 Mechanisms: Nucleophilic Carbonyl Addition Reactions
McMurry 1.6 Mechanisms: Nucleophilic Carbonyl Addition Reactions
lesson4 Mechanisms: Nucleophilic Carbonyl Addition Reactions, Nucleophilic Acyl Substitution Reactions, and Carbonyl Condensation Reactions
McMurry 1.6 Mechanisms: Nucleophilic Carbonyl Addition Reactions
McMurry 1.7 Mechanisms: Nucleophilic Acyl Substitution Reactions
McMurry 1.8 Mechanisms: Carbonyl Condensation Reactions
lesson5 Mechanisms: Various Reactions
McMurry 1.9 Mechanisms: Elimination Reactions
McMurry 1.10 Mechanisms: Radical Reactions
McMurry 1.11 Mechanisms: Pericyclic Reactions
McMurry 1.12 Mechanisms: Oxidation and Reduction
lesson6 Biomolecules: Enzymes and Cofactors
McMurry 2.6 Biomolecules: Enzymes and Cofactors
McMurry 2.7 High energy substances and their Conjugation Reactions
lesson7 Overview of lesson 1-6 for checking student's level of understanding
lesson8 Biosynthetic Pathway of Natural Products:
Chemistry of Natural Bioactive Substance, Chapter 1, Biosynthetic Pathway of Natural Products
lesson9 Fatty Acid Biosynthesis
McMurry 3.4 Fatty Acid Biosynthesis
lesson10 Terpenoid Biosynthesis, Steroid Biosynthesis
McMurry 3.5 Terpenoid Biosynthesis
McMurry 3.6 Steroid Biosynthesis
lesson11 Bioactive Compounds found in Mammals:
Chemistry of Natural Bioactive Substance, Chapter 2, Bioactive Compounds found in Mammals
lesson12 Bioactive Compounds found in Plants and their Functions against Human:
Chemistry of Natural Bioactive Substance, Chapter 3, Bioactive Compounds found in Plants and their Functions against Human
lesson13 Carcinogenesis and Antitumor Substance-1-
Chemistry of Natural Bioactive Substance, Chapter 5, Carcinogenesis and Antitumor Substance
lesson14 Carcinogenesis and Antitumor Substance-2-, Antibiotics-1-
Chemistry of Natural Bioactive Substance, Chapter 5, Carcinogenesis and Antitumor Substance
Chemistry of Natural Bioactive Substance, Chapter 6, Antibiotics
lesson15 Antibiotics-2-:
Chemistry of Natural Bioactive Substance, Chapter 6, Antibiotics

lesson7 Overview of lesson 1-6 for checking student's level of understanding
lesson 16; Examination will be held.
Report subjects will be announced when necessary.

[Notice] This lecture may be provided by online lectures when COVID-19 crisis still has a problem. I will let you know when necessary. 
Text/Reference
Books,etc.
「The Organic Chemistry of Biological Pathways The 2nd Edition」  John E. McMurry and Tadhg P. Begley
「Chemistry of Natural Bioactive Substance」 Masahiro Tada et al. Senkyosya 
PC or AV used in
Class,etc.
 
(More Details) Black board, short test, handout,  textbook 
Learning techniques to be incorporated  
Suggestions on
Preparation and
Review
Preparation: read the textbook
Review:  review short test and lecture 
Requirements  
Grading Method Examination (80%) Final examination (40%) Report (20%)  Total more than 60% will  earn a credit. 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Message  
Other   
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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