J1505030 Laboratory of Oral Function Sciences-Biochemistry,Physiology,Pharmacology-

Hiroshima University Syllabus

Japanese

Academic Year 2020Year School/Graduate School School of Dentistry Program of Dentistry

Lecture Code J1505030 Subject Classification Specialized Education

Subject Name 口腔機能学基礎実習

Subject Name
（Katakana）コウクウキノウガクキソジッシュウ

Subject Name in
English Laboratory of Oral Function Sciences-Biochemistry,Physiology,Pharmacology-

Instructor SUGITA MAKOTO,SHUKUNAMI CHISA,AGO YUKIO,KITAGAWA MITINORI,HIGUCHI SHINNOSUKE,SAKAYORI NOBUYUKI,HAYASHI IKUE,FUJIMOTO KATSUMI,ASANO SATOSHI

Instructor
(Katakana) スギタ　マコト,シュクナミ　チサ,アゴウ　ユキオ,キタガワ　ミチノリ,ヒグチ　シンノスケ,サカヨリ　ノブユキ,ハヤシ　イクエ,フジモト　カツミ,アサノ　サトシ

Campus Kasumi Semester/Term 3rd-Year, First Semester, First Semester

Days, Periods, and Classrooms (1st) Thur5-8,Fri5-8：DEN Training Rm 1

Lesson Style Practical Lesson Style
【More Details】 Lecture, Laboratory, Discussion, Presentation by students, Use of chemicals

Credits 2.0 Class Hours/Week 　 Language on Instruction B : Japanese／English

Course Level 3 : Undergraduate High-Intermediate

Course Area（Area） 26 : Biological and Life Sciences

Course Area（Discipline） 04 : Life Sciences

Eligible Students 3rd

Keywords Biochemistry
Physiology
Pharmacology

Special Subject for Teacher Education 　 Special Subject 　

Class Status
within Educational
Program
Criterion referenced
Evaluation Dentistry
（Knowledge and Understanding）
・Knowledge of basic behavior of a dentist.
（Abilities and Skills）
・Communication ability as a dentist.

Class Objectives
/Class Outline In this laboratory course, students carry out experiments about the physiological functions of the oral cavity and the whole body, the bioactive properties of proteins and small molecules, and the actions of drugs using laboratory animals in vivo, extracted organs, purified enzymes, and genes. Students learn experimental procedures and evaluation methods for experimental data. Textbooks and/or supplemental materials helpful for detailed understanding of experimental design are handed out before each laboratory practice.

Class Schedule Physiology:
1 Introduction and Explanation (Sugita, Kitagawa, Sakayori)
2,3,4 Physiology Laboratory 1 for A-E (Sugita, Kitagawa, Sakayori)
5 Examination (Sugita, Kitagawa, Sakayori)
6,7,8,9 Physiology Laboratory 2 for F and G (Sugita, Kitagawa, Sakayori)
10 Presentation of Laboratory 2 (Sugita, Kitagawa, Sakayori)
<Themes of Experiment and Practice>
A. Experiments on Electrocardiogram and Blood Pressure Measurement with Exercise
B. Measurements of Taste Threshold
C. Experiments on Tooth Topognosis
D. Experiments on Electromyogram
E. Experiments on Temperature Sensation
F. Measurements and Analyses of the Patterns of Mastication and Swallowing
G. Experiments on Bitter Taste Sensitivity and Genetic Polymorphism
H. Oral Presentation

Biochemistry:
11 Introduction and Explanation (Shukunami, Fujimoto, Hayashi)
12,13,14 Biochemistry Laboratory 1 (Shukunami, Fujimoto, Hayashi)
15,16,17 Biochemistry Laboratory 2 (Shukunami, Fujimoto, Hayashi)
18,19 Presentation (Shukunami, Fujimoto, Hayashi)
20 Examination (Shukunami, Fujimoto, Hayashi)
<Themes of Experiment and Practice>
A. Enzyme kinetics of alkaline phosphatase
B. Determination of protein concentration by the biuret method
C. SNP analysis of the ALDH2 gene
D. Oral Presentation

Pharmacology:
21 Introduction and Explanation (Ago, Asano)
22,23 Pharmacology Laboratory 1 (Ago, Asano)
24,25 Pharmacology Laboratory 2 (Ago, Asano)
26,27 Pharmacology Laboratory 3 (Ago, Asano)
28,29 Presentation (Ago, Asano)
30 Examination (Ago, Asano)
<Themes of Experiment and Practice>
A. Pain Relief Effects of NSAIDs
B. Pain Relief Effects of Morphine
C. Drug-Induced Contraction of Guinea-pig Ileum
D. Effects of Drugs on the Central Nervous System
E. Effects of Muscle Relaxant
F. Pain Relief Effects of Local Anesthetics
G. Oral Presentation

Text/Reference
Books,etc. Students can use the textbooks prepared by laboratories.

PC or AV used in
Class,etc. Textbooks, Handouts, Audio and Video teaching resources　

Suggestions on
Preparation and
Review Textbooks and/or supplemental materials helpful for detailed understanding of experimental design are handed out before each laboratory practice.

Requirements Students are not allowed to be absent from classes.
There are no supplementary classes for the student who is absent.
The student who is absent without notice may fail to earn the credit.

Grading Method Each student's achievement is assessed totally by attendance, relative performance in practice, experimental report submitted, presentation, and examination.
Each laboratory (Biochemistry, Physiology, or Pharmacology) evaluates students separately. Students must get passing marks in all the three laboratory classes to get the credit.

Practical Experience

Summary of Practical Experience and Class Contents based on it

Message Understanding of physiological functions of the oral cavity through laboratory classes.

Other

Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching.

Academic Year	2020Year	School/Graduate School	School of Dentistry Program of Dentistry
Lecture Code	J1505030	Subject Classification	Specialized Education
Subject Name	口腔機能学基礎実習
Subject Name （Katakana）	コウクウキノウガクキソジッシュウ
Subject Name in English	Laboratory of Oral Function Sciences-Biochemistry,Physiology,Pharmacology-
Instructor	SUGITA MAKOTO,SHUKUNAMI CHISA,AGO YUKIO,KITAGAWA MITINORI,HIGUCHI SHINNOSUKE,SAKAYORI NOBUYUKI,HAYASHI IKUE,FUJIMOTO KATSUMI,ASANO SATOSHI
Instructor (Katakana)	スギタ　マコト,シュクナミ　チサ,アゴウ　ユキオ,キタガワ　ミチノリ,ヒグチ　シンノスケ,サカヨリ　ノブユキ,ハヤシ　イクエ,フジモト　カツミ,アサノ　サトシ
Campus	Kasumi	Semester/Term	3rd-Year, First Semester, First Semester
Days, Periods, and Classrooms	(1st) Thur5-8,Fri5-8：DEN Training Rm 1
Lesson Style	Practical	Lesson Style 【More Details】	Lecture, Laboratory, Discussion, Presentation by students, Use of chemicals
Credits	2.0	Class Hours/Week		Language on Instruction	B : Japanese／English
Course Level	3 : Undergraduate High-Intermediate
Course Area（Area）	26 : Biological and Life Sciences
Course Area（Discipline）	04 : Life Sciences
Eligible Students	3rd
Keywords	Biochemistry Physiology Pharmacology
Special Subject for Teacher Education		Special Subject
Class Status within Educational Program
Criterion referenced Evaluation	Dentistry （Knowledge and Understanding）・Knowledge of basic behavior of a dentist. （Abilities and Skills）・Communication ability as a dentist.
Class Objectives /Class Outline	In this laboratory course, students carry out experiments about the physiological functions of the oral cavity and the whole body, the bioactive properties of proteins and small molecules, and the actions of drugs using laboratory animals in vivo, extracted organs, purified enzymes, and genes. Students learn experimental procedures and evaluation methods for experimental data. Textbooks and/or supplemental materials helpful for detailed understanding of experimental design are handed out before each laboratory practice.
Class Schedule	Physiology: 1 Introduction and Explanation (Sugita, Kitagawa, Sakayori) 2,3,4 Physiology Laboratory 1 for A-E (Sugita, Kitagawa, Sakayori) 5 Examination (Sugita, Kitagawa, Sakayori) 6,7,8,9 Physiology Laboratory 2 for F and G (Sugita, Kitagawa, Sakayori) 10 Presentation of Laboratory 2 (Sugita, Kitagawa, Sakayori) <Themes of Experiment and Practice> A. Experiments on Electrocardiogram and Blood Pressure Measurement with Exercise B. Measurements of Taste Threshold C. Experiments on Tooth Topognosis D. Experiments on Electromyogram E. Experiments on Temperature Sensation F. Measurements and Analyses of the Patterns of Mastication and Swallowing G. Experiments on Bitter Taste Sensitivity and Genetic Polymorphism H. Oral Presentation Biochemistry: 11 Introduction and Explanation (Shukunami, Fujimoto, Hayashi) 12,13,14 Biochemistry Laboratory 1 (Shukunami, Fujimoto, Hayashi) 15,16,17 Biochemistry Laboratory 2 (Shukunami, Fujimoto, Hayashi) 18,19 Presentation (Shukunami, Fujimoto, Hayashi) 20 Examination (Shukunami, Fujimoto, Hayashi) <Themes of Experiment and Practice> A. Enzyme kinetics of alkaline phosphatase B. Determination of protein concentration by the biuret method C. SNP analysis of the ALDH2 gene D. Oral Presentation Pharmacology: 21 Introduction and Explanation (Ago, Asano) 22,23 Pharmacology Laboratory 1 (Ago, Asano) 24,25 Pharmacology Laboratory 2 (Ago, Asano) 26,27 Pharmacology Laboratory 3 (Ago, Asano) 28,29 Presentation (Ago, Asano) 30 Examination (Ago, Asano) <Themes of Experiment and Practice> A. Pain Relief Effects of NSAIDs B. Pain Relief Effects of Morphine C. Drug-Induced Contraction of Guinea-pig Ileum D. Effects of Drugs on the Central Nervous System E. Effects of Muscle Relaxant F. Pain Relief Effects of Local Anesthetics G. Oral Presentation
Text/Reference Books,etc.	Students can use the textbooks prepared by laboratories.
PC or AV used in Class,etc.	Textbooks, Handouts, Audio and Video teaching resources
Suggestions on Preparation and Review	Textbooks and/or supplemental materials helpful for detailed understanding of experimental design are handed out before each laboratory practice.
Requirements	Students are not allowed to be absent from classes. There are no supplementary classes for the student who is absent. The student who is absent without notice may fail to earn the credit.
Grading Method	Each student's achievement is assessed totally by attendance, relative performance in practice, experimental report submitted, presentation, and examination. Each laboratory (Biochemistry, Physiology, or Pharmacology) evaluates students separately. Students must get passing marks in all the three laboratory classes to get the credit.
Practical Experience
Summary of Practical Experience and Class Contents based on it
Message	Understanding of physiological functions of the oral cavity through laboratory classes.
Other
Please fill in the class improvement questionnaire which is carried out on all classes. Instructors will reflect on your feedback and utilize the information for improving their teaching.

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