Hiroshima University Syllabus

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Academic Year 2020Year School/Graduate School School of Dentistry Program of Dentistry
Lecture Code J1504100 Subject Classification Specialized Education
Subject Name 免疫学
Subject Name
Subject Name in
タカハシ イチロウ,トビウメ ケイ
Campus Kasumi Semester/Term 2nd-Year,  Second Semester,  4Term
Days, Periods, and Classrooms (4T) Thur1-4:DEN Lecture Rm 7
Lesson Style Lecture Lesson Style
【More Details】
The lecture of immunology will be undertook in a dialogue-style dual language educational class. 
Credits 2.0 Class Hours/Week   Language on Instruction B : Japanese/English
Course Level 2 : Undergraduate Low-Intermediate
Course Area(Area) 27 : Health Sciences
Course Area(Discipline) 02 : Dental Sciences
Eligible Students Japanese as well as international foreign students, undergraduate 2nd grade.
Keywords Immune system, immune responses, innate immunity, adaptive immunity, autoimmunity, infectious immunity 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Criterion referenced
(Knowledge and Understanding)
・Knowledge regarding basic and clinical dental medicine
・Knowledge of life sciences
(Comprehensive Abilities)
・Rich humanity, understanding of professional responsibilities of a dentist, and general capabilities including basic knowledge, skills, and attitude required for putting such responsibilities into practice 
Class Objectives
/Class Outline
Immunity is defined as resistance to disease, specifically infectious or inflammatory disease. The collection of molecules, cells, and tissues that mediate resistance to infections is called the immune system, and the coordinated reaction of these molecules and cells is the immune response. Immunology is the study of the immune system and its responses to invading pathogens which enter via the mucosal and skin surfaces. The physiologic function of the immune system is to prevent infections and to eradicate established infections.

The following questions are addressed in this class:
• What types of immune responses protect individuals from infections?
• What are the important characteristics of mucosal as well as systemic immunity, and what mechanisms are responsible for these characteristics?
• How are the cells and tissues of the immune system organized to find microbes and respond to them in ways that lead to their elimination?
Class Schedule Introduction for crucial concepts of Immunity: Takahashi
The immune system: Takahashi
Cytokine: Takahashi
T-cell mediated adaptive immunity: Takahashi
B-cell mediated adaptive immunity: Takahashi
Immunological tolerance and Autoimmunity: Tobiume
Infection and Immunity: Takahashi
Vaccination: Kunisawa,Takahashi
Allergy: Kurashima,Takahashi
The mucosal immune system: Takahashi
Thymus and T cell development: Hamazaki,Takahashi
Antigen presentation: Takahashi
Leukocyte trafficking: Shimaoka,Takahashi
Innate immunity: Takeda,Takahashi
Tumor Immunity: Takahashi

A descriptive paper examination will be done once. 
Janeway's Immunobiology, 9th edition
Abbas, Lichtman, and Pillai, Cellular and Molecular Immunology, 9th edition
MacPherson's Exploring Immunology, concepts and evidence 
PC or AV used in
Power-point slides and several printed matters 
Suggestions on
Preparation and
The immunology class will be generally proceeded based on the recommended textbook (Basic Immunology and Immunobiology, 8th edition). 
Grading Method The evaluation will be done based on the results of the examination. 
Practical Experience  
Summary of Practical Experience and Class Contents based on it  
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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