Hiroshima University Syllabus

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Academic Year 2017Year School/Graduate School School of Engineering
Lecture Code K7368030 Subject Classification Specialized Education
Subject Name 情報分子生物学
Subject Name
Subject Name in
Molecular Bioinformatics
ナカシマダ ユタカ,タジマ タカヒサ
Campus Higashi-Hiroshima Semester/Term 3rd-Year,  Second Semester,  Second Semester
Days, Periods, and Classrooms (2nd) Fri3-4:ENG 114
Lesson Style Lecture Lesson Style
【More Details】
Lecture and practice 
Credits 2 Class Hours/Week   Language on Instruction B : Japanese/English
Course Level 4 : Undergraduate Advanced
Course Area(Area) 26 : Biological and Life Sciences
Course Area(Discipline) 26 : Biotechnology
Eligible Students Third grade
Keywords Genome information, Genomics, Proteomics, Metabolomics, System biology 
Special Subject for Teacher Education   Special Subject  
Class Status
within Educational
Criterion referenced
(Knowledge and Understanding)
・Acquisition of basic and advanced knowledge related to biotechnology and life science. (Target/Lecture class) 
Class Objectives
/Class Outline
Recently, technique for handling of bioinformatic data is required because of the accumulation of extensive bioinformatic data such as genome sequence. This class give the explaination about the aquisition, analysis and using of bioinformatic data in addition to bioethics.
Evaluation items in "Knowledge and Understanding" and  "Ability and Skill" are as follows.
"Knowledge and Understanding" in Biotechnology program: (C-3) Using of DNA and amino acid sequence information, rapid analysis of biomolecules, regulation of microbial fermentation, skills of software utilization for metabolic analysis, basic technique and aplication in computer programing. 
Class Schedule lesson1 Bioinformatics
lesson2 Molecular biology for bioinformatics 1 (Chapter1  1.2.1-1.2.5)
lesson3 Molecular biology for bioinformatics 2 (Chapter1  1.2.6-1.2.9)
lesson4 Sequence analysis of DNA and protein 1 - Homologous sequence, motif, function prediction (Chapter2 2.1.1-2.1.5)
lesson5 Sequence analysis of DNA and protein 2 - Computer practice (ClustalX, phylogenetic tree)
lesson6 Analysis of protein structure 1 - Purpose, structure classification (Chapter2 2.2.1-2.2.2)
lesson7 Analysis of protein structure 2 - Structural prediction(Chapter2 2.2.3-2.2.5)
lesson8 Genome sequence analysis 1 - Methodology, gene finding, fuctional prediction, classification (Chapter3 3.1.1-3.1.8)
lesson9 Genome sequence analysis 2 - Computer practice(Gene finding using NCBI database)
lesson10 Transcriptome (Chapter3 3.2.1)
lesson11 Proteome (Chapter3 3.2.2)
lesson12 Metabolic pathway analysis 1 - Metabolic database, metabolic pathway, metabolic pathway analysis, functional prediction (Chapter3 3.3.1-3.3.5)
lesson13 Metabolic pathway analysis 2 - Computer practice (Metabolic pathway analysis using KEGG database)
lesson14 System biology 1 - System identification, prediction and analysis (Chapter3 3.4.1-3.4.3)
lesson15  System biology 2 - System regulation - designing (Chapter3 3.4.4-3.4.5)

Final examination, reports 
Text book: 「はじめてのバイオインフォマティクス」、藤博幸(編)、講談社サイエンティフィク
Reference book: 「バイオインフォマティクス」、美宅成樹・榊佳之(編)、東京化学同人 (For furthrer understanding of methodology) 
PC or AV used in
Text,handout,Movie (Video/PC/other image document)Power point presentation, Text 
Suggestions on
Preparation and
Preparation and brushup based on the text book 
Grading Method Report (30%) and final examination (70%) are evaluated. 
Please fill in the class improvement questionnaire which is carried out on all classes.
Instructors will reflect on your feedback and utilize the information for improving their teaching. 
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